Gene Symbol |
GLRB
|
Entrez Gene |
2743
|
Alt Symbol |
HKPX2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
glycine receptor, beta
|
Other Description |
glycine receptor 58 kDa subunit|glycine receptor subunit beta|glycine receptor, beta subunit
|
Swissprots |
A8K3K2 P48167 F5GWE1 D3DP23
|
Accessions |
EAX04872 EAX04873 P48167 AF094754 AAC71033 AF094755 AAC71034 AK290617 BAF83306 BC022502 BC032635 AAH32635 CA437106 CD013911 DA168145 DA528659 DB479295 DQ890859 ABM81785 DQ894014 ABM84940 U33267 AAB37750 XM_011531876 XP_011530178 NM_000824 NP_000815 NM_001166060 NP_001159532 NM_001166061 NP_001159533
|
Function |
The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
|
Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
Neuroactive ligand-receptor interaction
|