Gene Symbol | GLRB |
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Entrez Gene | 2743 |
Alt Symbol | HKPX2 |
Species | Human |
Gene Type | protein-coding |
Description | glycine receptor, beta |
Other Description | glycine receptor 58 kDa subunit|glycine receptor subunit beta|glycine receptor, beta subunit |
Swissprots | A8K3K2 P48167 F5GWE1 D3DP23 |
Accessions | EAX04872 EAX04873 P48167 AF094754 AAC71033 AF094755 AAC71034 AK290617 BAF83306 BC022502 BC032635 AAH32635 CA437106 CD013911 DA168145 DA528659 DB479295 DQ890859 ABM81785 DQ894014 ABM84940 U33267 AAB37750 XM_011531876 XP_011530178 NM_000824 NP_000815 NM_001166060 NP_001159532 NM_001166061 NP_001159533 |
Function | The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |
GlyR β siRNA (h) - sc-42471 from Santa Cruz Biotechnology
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GlyR β shRNA Plasmid (h) - sc-42471-SH from Santa Cruz Biotechnology
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GlyR β shRNA (h) Lentiviral Particles - sc-42471-V from Santa Cruz Biotechnology
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GLRB RNAi - H00002743-R01 from Novus Biologicals
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MISSION® esiRNA - EHU029981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1824 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1824 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08301 from Sigma-Aldrich
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GLRB siRNA (Human) - CRH1827 from Cohesion Biosciences
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GLRB - MBS8214448 from MyBioSource
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shRNA set against Human GLRB (NM_000824.4) - SHH301974 from Creative biogene
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GLRB shRNA Plasmid (Human) - CHH1827 from Cohesion Biosciences
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GLRB miRNA 3'UTR clone - MiUTR3H-00928 from Creative biogene
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GLRB miRNA 3'UTR clone - MiUTR3H-00929 from Creative biogene
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GLRB miRNA 3'UTR clone - MiUTR3H-00930 from Creative biogene
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