CYBB

Gene Symbol	CYBB
Entrez Gene	1536
Alt Symbol	AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, IMD34, NOX2, p91-PHOX
Species	Human
Gene Type	protein-coding
Description	cytochrome b-245, beta polypeptide
Other Description	CGD91-phox|NADPH oxidase 2|cytochrome b(558) subunit beta|cytochrome b-245 heavy chain|cytochrome b558 subunit beta|heme-binding membrane glycoprotein gp91phox|neutrophil cytochrome b 91 kDa polypeptide|p22 phagocyte B-cytochrome|superoxide-generating NADPH oxidase heavy chain subunit
Swissprots	P04839 A8K138 Q2PP16
Accessions	AAL76082 ABC40728 ABY87073 ADQ73898 BAA34183 CAA29327 EAW59453 P04839 AK289753 BAF82442 AK301476 BAG62993 AK301491 BAG63002 AK304033 BAG64947 AK312929 BC032720 AAH32720 DA995835 DQ890878 ABM81804 DQ894032 ABM84958 S67289 AAB29151 X04011 CAA27635 XM_011543890 XP_011542192 NM_000397 NP_000388
Function	Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Detected in neutrophils (at protein level). {ECO:0000269|PubMed:19028840}.
Top Pathways	Leukocyte transendothelial migration, Phagosome, Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CYBB / NOX2 / gp91phox ELISA Kit (Sandwich ELISA) - LS-F8908 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Human CYBb ELISA Kit - abx151218 from Abbexa Category ELISA Kit Sensitivity 0.060 ng/ml Range 0.156 ng/ml - 10 ng/ml

Cytochrome b-245 Beta Polypeptide (CYBb), Human, ELISA Kit - SED308Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.055ng/mL Range 0.156-10ng/mL

Cytochrome b-245 heavy chain (CYBB), Human, ELISA Kit - E01C2212 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Cytochrome b 245 heavy chain (CYBB), ELISA Kit - MBS7250467 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS092173 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS066323 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS104482 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS104771 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS067144 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS072015 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS051039 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS056176 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS062591 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS074382 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS060054 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS092825 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS107429 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS096940 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS086201 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS071102 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS102108 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS093419 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS056055 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytochrome b-245 Beta Polypeptide, ELISA Kit - MBS090616 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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