| Gene Symbol | Gpihbp1 |
|---|---|
| Entrez Gene | 68453 |
| Alt Symbol | 1110002J19Rik, GPI-HBP1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | GPI-anchored HDL-binding protein 1 |
| Other Description | glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1|gpihbp1|high density lipoprotein-binding protein 1 |
| Swissprots | Q9D1N2 |
| Accessions | EDL29478 EDL29479 EDL29480 Q9D1N2 AB095543 BAC23061 AK003305 BAB22704 AK050431 BAC34253 BC061225 AAH61225 NM_026730 NP_081006 |
| Function | Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen and across endothelial cells. {ECO:0000269|PubMed:17403372, ECO:0000269|PubMed:17620854, ECO:0000269|PubMed:20620994}. |
| Subcellular Location | Apical cell membrane; Lipid-anchor, GPI- anchor. Basolateral cell membrane; Lipid-anchor, GPI-anchor. Cell membrane; Peripheral membrane protein; Extracellular side. |
| Tissue Specificity | Highly expressed on the luminal surface of capillary endothelium in heart, adipose tissue and skeletal muscle. Not detected in capillaries of the brain. Expressed at lower levels in lung and liver. {ECO:0000269|PubMed:12496272, ECO:0000269|PubMed:17403372}. |