Gene Symbol | Gpihbp1 |
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Entrez Gene | 68453 |
Alt Symbol | 1110002J19Rik, GPI-HBP1 |
Species | Mouse |
Gene Type | protein-coding |
Description | GPI-anchored HDL-binding protein 1 |
Other Description | glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1|gpihbp1|high density lipoprotein-binding protein 1 |
Swissprots | Q9D1N2 |
Accessions | EDL29478 EDL29479 EDL29480 Q9D1N2 AB095543 BAC23061 AK003305 BAB22704 AK050431 BAC34253 BC061225 AAH61225 NM_026730 NP_081006 |
Function | Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen and across endothelial cells. {ECO:0000269|PubMed:17403372, ECO:0000269|PubMed:17620854, ECO:0000269|PubMed:20620994}. |
Subcellular Location | Apical cell membrane; Lipid-anchor, GPI- anchor. Basolateral cell membrane; Lipid-anchor, GPI-anchor. Cell membrane; Peripheral membrane protein; Extracellular side. |
Tissue Specificity | Highly expressed on the luminal surface of capillary endothelium in heart, adipose tissue and skeletal muscle. Not detected in capillaries of the brain. Expressed at lower levels in lung and liver. {ECO:0000269|PubMed:12496272, ECO:0000269|PubMed:17403372}. |
GPIHBP1 CRISPR/Cas9 KO Plasmid (m) - sc-427056 from Santa Cruz Biotechnology
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GPIHBP1 HDR Plasmid (m) - sc-427056-HDR from Santa Cruz Biotechnology
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GPIHBP1 Double Nickase Plasmid (m) - sc-427056-NIC from Santa Cruz Biotechnology
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GPIHBP1 Double Nickase Plasmid (m2) - sc-427056-NIC-2 from Santa Cruz Biotechnology
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GPIHBP1 CRISPR Activation Plasmid (m) - sc-427056-ACT from Santa Cruz Biotechnology
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GPIHBP1 CRISPR Activation Plasmid (m2) - sc-427056-ACT-2 from Santa Cruz Biotechnology
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GPIHBP1 Lentiviral Activation Particles (m) - sc-427056-LAC from Santa Cruz Biotechnology
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GPIHBP1 Lentiviral Activation Particles (m2) - sc-427056-LAC-2 from Santa Cruz Biotechnology
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GPIHBP1 siRNA (m) - sc-145686 from Santa Cruz Biotechnology
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GPIHBP1 shRNA Plasmid (m) - sc-145686-SH from Santa Cruz Biotechnology
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GPIHBP1 shRNA (m) Lentiviral Particles - sc-145686-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN32680 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32680 from Sigma-Aldrich
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GPIHBP1 siRNA (Mouse) - CRM7642 from Cohesion Biosciences
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GPIHBP1 - MBS8239829 from MyBioSource
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shRNA set against Mouse GPI (NM_026730.1) - SHH305902 from Creative biogene
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shRNA set against Mouse Gpihbp1(NM_026730.1) - SHH096491 from Creative biogene
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Mouse GPIHBP1 siRNA - orb287118 from Biorbyt
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GPIHBP1 shRNA Plasmid (Mouse) - CHM7642 from Cohesion Biosciences
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GPIHBP1 miRNA 3'UTR clone - MiUTR1M-05272 from Creative biogene
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