Gene Symbol | TNPO3 |
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Entrez Gene | 23534 |
Alt Symbol | IPO12, LGMD1F, MTR10A, TRN-SR, TRN-SR2, TRNSR |
Species | Human |
Gene Type | protein-coding |
Description | transportin 3 |
Other Description | imp12|importin 12|limb girdle muscular dystrophy 1F (autosomal dominant)|transportin-3|transportin-SR |
Swissprots | C9IZM0 Q9Y3R2 Q6NUM1 A4D1K9 Q9Y5L0 Q96GU9 Q96G71 |
Accessions | EAL24106 EAW83708 EAW83709 EAW83710 Q9Y5L0 AF145029 AAD38537 AJ133769 CAB42643 AK001263 BAG50881 AK022910 BAG51133 AK225999 AK312580 BAG35474 AW051835 BC009221 AAH09221 BC009923 BC068530 BC156517 AAI56518 BC172512 AAI72512 BQ774864 CB992781 DA188633 DA720844 DA773316 XM_011515989 XP_011514291 NM_001191028 NP_001177957 NM_012470 NP_036602 NR_034053 |
Function | Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins RBM4, SFRS1 and SFRS2, by recognizing phosphorylated RS domains. {ECO:0000269|PubMed:10366588, ECO:0000269|PubMed:10713112, ECO:0000269|PubMed:11517331, ECO:0000269|PubMed:12628928}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:10713112}. Nucleus {ECO:0000269|PubMed:10713112}. |
Tissue Specificity | Expressed in skeletal muscle. {ECO:0000269|PubMed:23667635}. |
Importin-12 (C-2) - sc-376346 from Santa Cruz Biotechnology
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Importin-12 (H-300) - sc-98826 from Santa Cruz Biotechnology
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Importin-12 (T-14) - sc-104331 from Santa Cruz Biotechnology
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Importin-12 (N-15) - sc-104330 from Santa Cruz Biotechnology
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Anti-TNPO3 antibody - ab71388 from Abcam
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Anti-TNPO3 antibody [3152C2a] - ab54353 from Abcam
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Anti-TNPO3 antibody [EPR5264] - ab109386 from Abcam
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Anti-TNPO3 antibody - C-terminal - ab186964 from Abcam
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Anti-Transportin-SR / TNPO3 Antibody - LS-C76518 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (aa799-828, AP) - LS-C241990 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (aa799-828, APC) - LS-C241991 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (aa799-828, FITC) - LS-C241992 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (aa799-828, Biotin) - LS-C241993 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (aa799-828, PE) - LS-C241994 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (aa799-828, Azide-free, HRP) - LS-C247104 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (aa799-828) - LS-C330244 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (N-Terminus) - LS-C53298 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (N-Terminus) - LS-C53297 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (clone 3152C2a) - LS-C184484 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (aa664-713) - LS-C206170 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (C-Terminus, clone EPR5264) - LS-C138591 from LifeSpan Bioscience
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Anti-Transportin-SR / TNPO3 Antibody (clone 3152C2a) - LS-C342524 from LifeSpan Bioscience
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TNPO3 Antibody - NBP1-81585 from Novus Biologicals
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TNPO3 Antibody - NBP1-76374 from Novus Biologicals
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Anti-TNPO3 (ab1) antibody produced in rabbit - PRS4597 from Sigma-Aldrich
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