Gene Symbol | TJP1 |
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Entrez Gene | 403752 |
Alt Symbol | ZO-1, ZO1 |
Species | Dog |
Gene Type | protein-coding |
Description | tight junction protein 1 (zona occludens 1) |
Other Description | tight junction protein ZO-1|zona occludens protein 1|zonula occludens 1|zonula occludens protein 1 |
Swissprots | O97758 |
Accessions | AAG43398 O97758 U55935 AAD11529 NM_001003140 NP_001003140 |
Function | The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cell junction {ECO:0000250}. Cell junction, gap junction {ECO:0000250}. Note=Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact. Detected at the leading edge of migrating and wounded cells (By similarity). {ECO:0000250}. |
Top Pathways | Adherens junction, Tight junction, Gap junction, Salmonella infection |
Canine TJP1 ELISA Kit - CT0226 from NeoScientific
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tight junction protein 1 (ZO1) , ELISA Kit - MBS706128 from MyBioSource
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Canine Tight Junction Protein 1 ELISA - E08T0219 from BlueGene Biotech
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tight junction protein 1 (zona occludens 1) , ELISA Kit - MBS2602867 from MyBioSource
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Canine TJP1 ELISA Kit - E103628 from Biobool
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TJP1 ELISA Kit (Rat) (OKCA01006) - OKCA01006 from Aviva Systems Biology
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Canine TJP1 ELISA Kit - ECT0226 from ABclonal
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