| Gene Symbol | MIF |
|---|---|
| Entrez Gene | 100857237 |
| Alt Symbol | - |
| Species | Chicken |
| Gene Type | protein-coding |
| Description | macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
| Other Description | L-dopachrome isomerase|L-dopachrome tautomerase|Phenylpyruvate tautomerase|macrophage migration inhibitory factor |
| Swissprots | Q02960 |
| Accessions | Q02960 AL585053 BU431911 M95776 AAA48939 XM_003642234 XP_003642282 NM_001305091 NP_001292020 |
| Function | Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti- inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial antigens (By similarity). {ECO:0000250}. |
| Top Pathways | Tyrosine metabolism, Phenylalanine metabolism |
Macrophage migration inhibitory factor, MIF, Chicken, ELISA Kit - E0698c from ARP American Research Products
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Chicken MIF ELISA Kit - CKM0216 from NeoScientific
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Chicken MIF (Macrophage Migration Inhibitory Factor) ELISA Kit - E-EL-Ch0273 from Elabscience
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Chicken Macrophage MigRation Inhibitory Factor ELISA - E12M0209 from BlueGene Biotech
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Chicken AMH (Anti-Mullerian Hormone) ELISA Kit - E-EL-Ch1862 from Iwai North America Inc.
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Chicken MIF (Macrophage Migration Inhibitory Factor) ELISA Kit - E-EL-Ch0273 from Iwai North America Inc.
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Chicken S100A8 (S100 Calcium Binding Protein A8/Calgranulin A) ELISA Kit - E-EL-Ch0344 from Iwai North America Inc.
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Chicken S100A9 (S100 Calcium Binding Protein A9) ELISA Kit - E-EL-Ch1105 from Iwai North America Inc.
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Chicken MIF ELISA Kit - E089711 from Biobool
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Chicken MIF ELISA Kit - ECKM0216 from ABclonal
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Macrophage migration inhibitory factor, ELISA Kit - MBS2884255 from MyBioSource
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