TNFRSF14

Gene Symbol TNFRSF14
Entrez Gene 8764
Alt Symbol ATAR, CD270, HVEA, HVEM, LIGHTR, TR2
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 14
Other Description CD40-like protein|herpes virus entry mediator A|tumor necrosis factor receptor superfamily member 14|tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)|tumor necrosis factor receptor-like gene2
Swissprots Q9UM65 B9DI89 B3KW30 Q96J31 Q8N634 Q6IB95 Q8WXR1 Q92956
Accessions AAR23264 EAW56089 EAW56090 EAW56091 EAW56092 EAW56093 EAW56094 Q92956 AB208808 BAD92045 AF153978 AAF75588 AF373877 AAL47717 AF373878 AAL47718 AK124010 BAG53992 AK130172 BAC85297 AK300515 BAG62227 AK303468 BAG64508 AK310076 AY358879 AAQ89238 BC002794 AAH02794 BC018882 BC029848 AAH29848 BM981793 BX343044 CD366981 CR456909 CAG33190 DC383433 DQ893000 ABM83926 DQ896755 ABM87754 U70321 AAB58354 U81232 AAD00505 XM_006711019 XP_006711082 XM_006711020 XP_006711083 XM_006724947 XP_006725010 XM_006724948 XP_006725011 XM_011542383 XP_011540685 XM_011546411 XP_011544713 XR_426638 XR_430632 NM_001297605 NP_001284534 NM_003820 NP_003811
Function Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. {ECO:0000269|PubMed:8898196}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Widely expressed, with the highest expression in lung, spleen and thymus.
Top Pathways Cytokine-cytokine receptor interaction, Herpes simplex infection

HVEM CRISPR/Cas9 KO Plasmid (h) - sc-402104 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVEM HDR Plasmid (h) - sc-402104-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVEM Double Nickase Plasmid (h) - sc-402104-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVEM Double Nickase Plasmid (h2) - sc-402104-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVEM CRISPR Activation Plasmid (h) - sc-402104-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVEM CRISPR Activation Plasmid (h2) - sc-402104-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVEM Lentiviral Activation Particles (h) - sc-402104-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVEM Lentiviral Activation Particles (h2) - sc-402104-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVEM siRNA (h) - sc-43855 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HVEM shRNA Plasmid (h) - sc-43855-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HVEM shRNA (h) Lentiviral Particles - sc-43855-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HVEM/TNFRSF14 RNAi - H00008764-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU080621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21747 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21747 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04142 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04142

TNFRSF14 siRNA (Human) - CRH5773 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFRSF14 - MBS8212306 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TNFRSF14 (NM_003820.2) - SHH431932 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TNFRSF14(NM_003820.2) - SHL084626 from Creative biogene

Category siRNA
Species Reactivities Human

Human TNFRSF14 siRNA - orb266275 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFRSF14 shRNA Plasmid (Human) - CHH5773 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TNFRSF14 miRNA 3'UTR clone - MiUTR1H-10595 from Creative biogene

Species Reactivities Human
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