Gene Symbol | EDARADD |
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Entrez Gene | 128178 |
Alt Symbol | ECTD11A, ECTD11B, ED3, EDA3 |
Species | Human |
Gene Type | protein-coding |
Description | EDAR-associated death domain |
Other Description | EDAR-associated death domain protein|crinkled homolog|ectodysplasia A receptor associated death domain|ectodysplasin A receptor associated adapter protein|ectodysplasin-A receptor-associated adapter protein |
Swissprots | B1AL54 B9ZVW5 A8K7B5 Q5VYJ7 A2VCK5 Q8WWZ3 |
Accessions | AAK40285 AAK40286 AER00472 EAW70047 EAW70048 EAW70049 EAW70050 EAW70051 EAW70052 Q8WWZ3 AK096339 AK290862 BAF83551 AK291930 BAF84619 AK314634 BAG37197 AY028913 AAK40287 AY028914 AAK40288 AY071862 AAL60590 BC006533 BC046928 BC114557 BC114560 BC128082 AAI28083 NM_080738 NP_542776 NM_145861 NP_665860 |
Function | Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF- kappa-B. {ECO:0000269|PubMed:11882293}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
Tissue Specificity | Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis. |
EDARADD CRISPR/Cas9 KO Plasmid (h) - sc-414316 from Santa Cruz Biotechnology
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EDARADD HDR Plasmid (h) - sc-414316-HDR from Santa Cruz Biotechnology
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EDARADD Double Nickase Plasmid (h) - sc-414316-NIC from Santa Cruz Biotechnology
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EDARADD Double Nickase Plasmid (h2) - sc-414316-NIC-2 from Santa Cruz Biotechnology
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EDARADD CRISPR Activation Plasmid (h) - sc-414316-ACT from Santa Cruz Biotechnology
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EDARADD CRISPR Activation Plasmid (h2) - sc-414316-ACT-2 from Santa Cruz Biotechnology
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EDARADD Lentiviral Activation Particles (h) - sc-414316-LAC from Santa Cruz Biotechnology
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EDARADD Lentiviral Activation Particles (h2) - sc-414316-LAC-2 from Santa Cruz Biotechnology
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EDARADD siRNA (h) - sc-88807 from Santa Cruz Biotechnology
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EDARADD shRNA Plasmid (h) - sc-88807-SH from Santa Cruz Biotechnology
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EDARADD shRNA (h) Lentiviral Particles - sc-88807-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU116331 from Sigma-Aldrich
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MISSION® esiRNA - EHU116201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7646 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7646 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10920 from Sigma-Aldrich
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EDARADD siRNA (Human) - CRJ4943 from Cohesion Biosciences
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EDARADD - MBS827743 from MyBioSource
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shRNA set against Human EDARADD (NM_080738.3) - SHH283073 from Creative biogene
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shRNA set against Human EDARADD(NM_145861.2) - SHH023375 from Creative biogene
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shRNA set against Human EDARADD(NM_080738.3) - SHH023411 from Creative biogene
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Human EDARADD siRNA - orb275444 from Biorbyt
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EDARADD shRNA Plasmid (Human) - CHJ4943 from Cohesion Biosciences
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EDARADD miRNA 3'UTR clone - MiUTR1H-03101 from Creative biogene
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EDARADD miRNA 3'UTR clone - MiUTR1H-03102 from Creative biogene
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