Gene Symbol | CAV1 |
---|---|
Entrez Gene | 403980 |
Alt Symbol | caveolin 1 |
Species | Dog |
Gene Type | protein-coding |
Description | caveolin 1, caveolae protein, 22kDa |
Other Description | caveolin-1|vesicular integral-membrane protein VIP21 |
Swissprots | P33724 A0M8U8 |
Accessions | AAR16266 CAA78151 P33724 U47060 AAA87050 XM_005628347 XP_005628404 NM_001003296 NP_001003296 |
Function | Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G- protein alpha subunits and can functionally regulate their activity. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. |
Subcellular Location | Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft {ECO:0000250}. Note=Colocalized with DPP4 in membrane rafts (By similarity). Potential hairpin-like structure in the membrane. Membrane protein of caveolae. {ECO:0000250}. |
Top Pathways | Focal adhesion, Endocytosis, Bacterial invasion of epithelial cells, Proteoglycans in cancer |
Dog CAV1 protein - orb245777 from Biorbyt
|
||||||||||
Recombinant Caveolin 1 (CAV1) - RPA214Ca01 from Cloud-clone
|
||||||||||
Recombinant Dog Caveolin-1(CAV1) - CSB-EP004571DO CSB-BP004571DO CSB-MP004571DO from Cusabio
|
||||||||||
Recombinant Dog Caveolin-1(CAV1) - CSB-YP004571DO from Cusabio
|
||||||||||
Caveolin-1, Recombinant Protein - MBS949563 from MyBioSource
|
||||||||||
CAV1 Recombinant Protein (OPCA02615) - OPCA02615 from Aviva Systems Biology
|
||||||||||
Recombinant dog Caveolin-1 - AP72475 from Signalway Antibody
|
||||||||||
Caveolin-1, Recombinant Protein - MBS9422219 from MyBioSource
|
||||||||||
Recombinant Dog Caveolin-1 (CAV1) - RPC24551 from Biomatik
|