Gene Symbol | NLRP12 |
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Entrez Gene | 91662 |
Alt Symbol | CLR19.3, FCAS2, NALP12, PAN6, PYPAF7, RNO, RNO2 |
Species | Human |
Gene Type | protein-coding |
Description | NLR family, pyrin domain containing 12 |
Other Description | NACHT, LRR and PYD domains-containing protein 12|PYRIN-containing APAF1-like protein 7|monarch 1|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12|regulated by nitric oxide |
Swissprots | B3KTE7 Q9BY26 A8MTQ2 Q8NEU4 P59046 |
Accessions | EAW72151 EAW72152 EAW72153 EAW72154 EAW72155 EAW72156 EAW72157 P59046 AF231021 AAK14942 AK095460 BAG53059 AK290772 BAF83461 AY095146 AAM18227 AY116204 AAM75142 AY116205 AAM75143 AY116206 AAM75144 AY116207 AAM75145 AY154467 AAO18163 BC028069 AAH28069 DA619102 DQ891084 ABM82010 DQ894266 ABM85192 XM_011527478 XP_011525780 XM_011527479 XP_011525781 XM_011527480 XP_011525782 XM_011527481 XP_011525783 XM_011527482 XP_011525784 XM_011527483 XP_011525785 NM_001277126 NP_001264055 NM_001277129 NP_001264058 NM_144687 NP_653288 NM_033297 |
Function | May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Detected only in peripheral blood leukocytes, predominantly in eosinophils and granulocytes, and at lower levels in monocytes. {ECO:0000269|PubMed:11167794}. |
PYPAF7 (A-3) - sc-390666 from Santa Cruz Biotechnology
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PYPAF7 (N-13) - sc-30645 from Santa Cruz Biotechnology
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PYPAF7 (C-12) - sc-30647 from Santa Cruz Biotechnology
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PYPAF7 (R-15) - sc-30650 from Santa Cruz Biotechnology
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Anti-NALP12 antibody - ab105409 from Abcam
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Anti-NALP12 antibody - ab100863 from Abcam
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Anti-NALP12 antibody - ab93113 from Abcam
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Anti-NALP12 antibody - ab57906 from Abcam
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Anti-NALP12 antibody - Carboxyterminal end - ab64928 from Abcam
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Anti-NLRP12 Antibody - LS-C73147 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (aa190-208) - LS-C148286 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (aa930-945) - LS-C149001 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (clone 228CT4.1.3, AP) - LS-C232213 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (clone 228CT4.1.3, Biotin) - LS-C232214 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (clone 228CT4.1.3, FITC) - LS-C232215 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (clone 228CT4.1.3, APC) - LS-C232216 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (clone 228CT4.1.3, PE) - LS-C232218 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (aa446-459) - LS-C205039 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (C-Terminus, AP) - LS-C245105 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (C-Terminus, Biotin) - LS-C245106 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (C-Terminus, APC) - LS-C245107 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (C-Terminus, FITC) - LS-C245108 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (C-Terminus, PE) - LS-C245110 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (aa183-212, AP) - LS-C246615 from LifeSpan Bioscience
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Anti-NLRP12 Antibody (aa183-212, Biotin) - LS-C246616 from LifeSpan Bioscience
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