NAIP

Gene Symbol	NAIP
Entrez Gene	4671
Alt Symbol	BIRC1, NLRB1, psiNAIP
Species	Human
Gene Type	protein-coding
Description	NLR family, apoptosis inhibitory protein
Other Description	baculoviral IAP repeat-containing protein 1|neuronal apoptosis inhibitory protein|nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1|psi neuronal apoptosis inhibitory protein
Swissprots	Q99796 E9PHD1 Q13730 O75857 B9EG72 Q13075 Q8TDZ4 Q59GI6
Accessions	AAC52047 AAC62261 EAW50510 Q13075 AB048534 BAB87181 AB209123 BAD92360 AK124511 AK295115 BAG58144 AK309627 AK311046 BC136273 AAI36274 BC143761 AAI43762 DQ786305 U19251 AAC52045 XM_005248523 XP_005248580 XM_005248524 XP_005248581 XM_005276800 XP_005276857 XM_005276801 XP_005276858 XM_005276802 XP_005276859 XM_006714626 XP_006714689 XM_006714629 XP_006714692 XM_006714630 XP_006714693 XM_006725453 XP_006725516 XM_006725456 XP_006725519 XM_006725457 XP_006725520 XM_006725458 XP_006725521 XM_006725459 XP_006725522 XM_006726219 XP_006726282 XM_006726222 XP_006726285 XM_011543409 XP_011541711 XM_011543410 XP_011541712 XM_011543411 XP_011541713 XM_011543412 XP_011541714 XM_011543413 XP_011541715 XM_011546973 XP_011545275 XM_011546974 XP_011545276 XM_011546975 XP_011545277 XM_011546976 XP_011545278 XM_011546977 XP_011545279 XM_011546978 XP_011545280 XM_011546979 XP_011545281 XM_011547345 XP_011545647 XM_011547346 XP_011545648 XM_011547347 XP_011545649 XM_011547348 XP_011545650 XM_011547349 XP_011545651 NM_004536 NP_004527 NM_022892 NP_075043
Function	Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as a mediator of neuronal survival in pathological conditions. Prevents motor- neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.
Tissue Specificity	Expressed in motor neurons, but not in sensory neurons. Found in liver and placenta, and to a lesser extent in spinal cord.
Top Pathways	NOD-like receptor signaling pathway, Legionellosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NAIP peptide - ab39795 from Abcam Category Peptide Species Human

Human NAIP protein fragment - ab158950 from Abcam Category Protein Source Wheat germ Species Human

BIRC1 / NAIP Antibody Blocking Peptide - LS-E27309 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BIRC1 / NAIP Antibody Blocking Peptide - LS-E30068 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human NAIP Protein - H00004671-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NAIP Blocking Peptide - NBP1-77196PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

NAIP blocking peptide - GTX88182-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

BIRC1 protein (His tag) - 80R-4192 from Fitzgerald Category Protein Prices $1,995.00 Sizes 1 mg Source E.coli Species Human

BIRC1 protein (His tag) - 80R-4193 from Fitzgerald Category Protein Prices $1,295.00 Sizes 500 µg Source E.coli Species Human

NAIP Blocking Peptide - 33R-10672 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

NAIP Peptide - AC21-2131-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NAIP - H00004671-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NAIP - H00004671-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NAIP Control Peptide - AP30574CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

NAIP Peptide - 3315P from ProSci Category Peptide Species Human

NAIP Peptide - 42-537P from ProSci Category Peptide

Recombinant Neuronal Apoptosis Inhibitory Protein (NAIP) - RPB524Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Neuronal Apoptosis Inhibitory Protein (NAIP) - RPB524Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Neuronal Apoptosis Inhibitory Protein (NAIP) - RPB524Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Baculoviral IAP repeat-containing protein 1(NAIP) ,partial - CSB-YP615662HU CSB-EP615662HU CSB-BP615662HU CSB-MP615662HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NAIP Blocking Peptide - 3228BP-50 from Biovision Category Peptide Prices $95.00 Sizes 50 µg

NAIP, Peptide - MBS843969 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

NAIP, Peptide - MBS427227 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

NAIP Recombinant Protein Antigen - NBP1-88596PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Recombinant human Baculoviral IAP repeat-containing protein 1 - CSB-EP615662HU from Cusabio Category Protein Source E.coli Species Human

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