| Gene Symbol |
PPP4R1
|
| Entrez Gene |
9989
|
| Alt Symbol |
MEG1, PP4(Rmeg), PP4R1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein phosphatase 4, regulatory subunit 1
|
| Other Description |
serine/threonine phosphatase 4|serine/threonine-protein phosphatase 4 regulatory subunit 1
|
| Swissprots |
Q9UNQ7 Q99774 Q8TF05
|
| Accessions |
EAX01598 EAX01599 EAX01600 Q8TF05 AF100744 AAD43008 AF111106 AAD09818 AF200478 AAL78298 AI621152 AK025509 AK027064 AK292538 BAF85227 AK293869 BAG57259 AK295533 BAG58445 AK315106 BAG37566 AY486333 AAS59409 BC060829 AAH60829 DR006046 U79267 AAB50211 XM_011525775 XP_011524077 XM_011525776 XP_011524078 XM_011525777 XP_011524079 XM_011525778 XP_011524080 XM_011525779 XP_011524081 XR_935075 NM_001042388 NP_001035847 NM_005134 NP_005125 NR_052003
|
| Function |
Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. {ECO:0000269|PubMed:15805470}.
|
| Tissue Specificity |
Widely expressed with high expression in cultured mesangial cells. Isoform 1 and isoform 2 are expressed in renal tissues. {ECO:0000269|PubMed:11729228}.
|