Gene Symbol | PPP4R1 |
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Entrez Gene | 9989 |
Alt Symbol | MEG1, PP4(Rmeg), PP4R1 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 4, regulatory subunit 1 |
Other Description | serine/threonine phosphatase 4|serine/threonine-protein phosphatase 4 regulatory subunit 1 |
Swissprots | Q9UNQ7 Q99774 Q8TF05 |
Accessions | EAX01598 EAX01599 EAX01600 Q8TF05 AF100744 AAD43008 AF111106 AAD09818 AF200478 AAL78298 AI621152 AK025509 AK027064 AK292538 BAF85227 AK293869 BAG57259 AK295533 BAG58445 AK315106 BAG37566 AY486333 AAS59409 BC060829 AAH60829 DR006046 U79267 AAB50211 XM_011525775 XP_011524077 XM_011525776 XP_011524078 XM_011525777 XP_011524079 XM_011525778 XP_011524080 XM_011525779 XP_011524081 XR_935075 NM_001042388 NP_001035847 NM_005134 NP_005125 NR_052003 |
Function | Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. {ECO:0000269|PubMed:15805470}. |
Tissue Specificity | Widely expressed with high expression in cultured mesangial cells. Isoform 1 and isoform 2 are expressed in renal tissues. {ECO:0000269|PubMed:11729228}. |
PP4R1 CRISPR/Cas9 KO Plasmid (h) - sc-411399 from Santa Cruz Biotechnology
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PP4R1 HDR Plasmid (h) - sc-411399-HDR from Santa Cruz Biotechnology
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PP4R1 Double Nickase Plasmid (h) - sc-411399-NIC from Santa Cruz Biotechnology
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PP4R1 Double Nickase Plasmid (h2) - sc-411399-NIC-2 from Santa Cruz Biotechnology
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PP4R1 CRISPR Activation Plasmid (h) - sc-411399-ACT from Santa Cruz Biotechnology
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PP4R1 CRISPR Activation Plasmid (h2) - sc-411399-ACT-2 from Santa Cruz Biotechnology
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PP4R1 Lentiviral Activation Particles (h) - sc-411399-LAC from Santa Cruz Biotechnology
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PP4R1 Lentiviral Activation Particles (h2) - sc-411399-LAC-2 from Santa Cruz Biotechnology
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PP4R1 siRNA (h) - sc-62848 from Santa Cruz Biotechnology
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PP4R1 shRNA Plasmid (h) - sc-62848-SH from Santa Cruz Biotechnology
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PP4R1 shRNA (h) Lentiviral Particles - sc-62848-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU041601 from Sigma-Aldrich
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MISSION® esiRNA - EHU116471 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP1040 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP1041 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0667 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP1039 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0669 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0668 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17310 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17310 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07471 from Sigma-Aldrich
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PPP4R1 siRNA (Human) - CRH6721 from Cohesion Biosciences
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PPP4R1 RNAi - H00009989-R01 from Novus Biologicals
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shRNA set against Human PPP4R1 (NM_005134.3) - SHH381604 from Creative biogene
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