TCHH

Gene Symbol TCHH
Entrez Gene 7062
Alt Symbol THH, THL, TRHY
Species Human
Gene Type protein-coding
Description trichohyalin
Other Description -
Swissprots Q5VUI3 Q07283
Accessions AAA65582 AAB27489 CCQ43387 Q07283 AK307946 AY827491 AAX12418 BC131826 AAI31827 BC131827 AAI31828 NM_007113 NP_009044
Function Intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the epidermis. It later becomes cross-linked to KIF by isodipeptide bonds. It may serve as scaffold protein, together with involucrin, in the organization of the cell envelope or even anchor the cell envelope to the KIF network. It may be involved in its own calcium-dependent postsynthetic processing during terminal differentiation.
Tissue Specificity Found in the hard keratinizing tissues such as the inner root sheath (IRS) of hair follicles and medulla, and in the filiform papillae of dorsal tongue epithelium.

Panoply™ Human TCHH Knockdown Stable Cell Line - CSC-DC015731 from Creative biogene

Category Cell Line
Species Human
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