C9orf3

Gene Symbol C9orf3
Entrez Gene 84909
Alt Symbol AOPEP, AP-O, APO, C90RF3, ONPEP
Species Human
Gene Type protein-coding
Description chromosome 9 open reading frame 3
Other Description aminopeptidase O
Swissprots Q96SS1 Q5T9B4 Q96M23 Q5T9B1 Q8WUL6 Q5T9B3 Q8N6M6
Accessions EAW92618 EAW92619 EAW92620 EAW92621 EAW92622 EAW92623 Q8N6M6 AF043896 AF043897 AI982632 AJ560639 CAD90259 AK027581 BAB55210 AK057450 BAB71491 AK098242 AK130021 AK296699 BAG59293 AK296782 BAG59360 AK298959 BAG61055 AK300486 BAG62201 AL137535 BC020194 AAH20194 BC029616 AAH29616 BC042892 BP274281 BQ448239 BX099259 BX648970 DA222106 DA521148 XM_005252284 XP_005252341 XM_006717306 XP_006717369 XM_011519119 XP_011517421 XM_011519120 XP_011517422 XM_011519121 XP_011517423 XM_011519122 XP_011517424 XM_011519123 XP_011517425 XM_011519124 XP_011517426 XM_011519125 XP_011517427 XM_011519126 XP_011517428 XM_011519127 XP_011517429 XM_011519128 XP_011517430 XM_011519129 XP_011517431 XM_011519130 XP_011517432 XM_011519131 XP_011517433 XM_011519132 XP_011517434 XM_011519133 XP_011517435 XM_011519134 XP_011517436 XM_011519135 XP_011517437 XR_929852 XR_929853 XR_929854 XR_929855 XR_929856 XR_929857 XR_929858 NM_001193329 NP_001180258 NM_001193331 NP_001180260 NM_032823 NP_116212 NM_001193330
Function Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart. {ECO:0000269|PubMed:15687497}.
Subcellular Location Cytoplasm {ECO:0000305}.
Tissue Specificity Predominantly expressed in pancreas, placenta, liver, testis and heart. Expressed at lower level in brain, lung and kidney. {ECO:0000269|PubMed:15687497}.

APO (P-17) - sc-241832 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-C9orf3 antibody - ab69211 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-C9orf3 antibody (ab69211) at 1/500 dilutionLane 1 : C9orf3 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-AOPEP / Aminopeptidase O Antibody (aa215-242, APC) - LS-C212728 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AOPEP / Aminopeptidase O Antibody (aa215-242, Biotin) - LS-C212729 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AOPEP / Aminopeptidase O Antibody (aa1-819) - LS-C68906 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-AOPEP / Aminopeptidase O Antibody (aa215-242, AP) - LS-C212727 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AOPEP / Aminopeptidase O Antibody (aa215-242, PE) - LS-C212732 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AOPEP / Aminopeptidase O Antibody (aa215-242, FITC) - LS-C212730 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AOPEP / Aminopeptidase O Antibody (aa215-242, Azide-free, HRP) - LS-C212731 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AOPEP / Aminopeptidase O Antibody (aa214-242) - LS-C319504 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AOPEP / Aminopeptidase O Antibody - LS-C306272 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-AOPEP / Aminopeptidase O Antibody (aa215-242) - LS-C159080 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
AOPEP Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The AOPEP antibody detected the AOPEP protein (arrow).

Aminopeptidase O/ONPEP Antibody - AF4647 from Novus Biologicals

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

Aminopeptidase O/ONPEP Antibody (562912) - MAB4647 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 562912

Aminopeptidase O/ONPEP Antibody - NBP1-89066 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: aminopeptidase O Antibody [NBP1-89066] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Aminopeptidase O/ONPEP Antibody - H00084909-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Aminopeptidase O/ONPEP Antibody [H00084909-B01P] - Analysis of C9orf3 expression in transfected 293T cell line by C9orf3 polyclonal antibody. Lane 1: C9orf3 transfected lysate(79.2 KDa). Lane 2: Non-transfected lysate.

Rabbit Anti-C9orf3 Polyclonal Antibody - bs-15325R from Bioss

Host Rabbit
Clonality Polyclonal

Anti-C9orf3 antibody produced in rabbit - HPA004633 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-C9orf3: <B>Cat. No. HPA004633</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing granular cytoplasmic staining of cells in tubuli.

Anti-C9ORF3 antibody produced in mouse - SAB1408134 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-C9orf3: <B>Cat. No. SAB1408134</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~79.2 kDa using C9orf3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

AOPEP-Antibody-N-term - AP17505a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
AOPEP Antibody (N-term) (Cat. #AP17505a) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the AOPEP antibody detected the AOPEP protein (arrow).

AOPEP Antibody - N-terminal region (OAAB12936) - OAAB12936 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti -AOPEP (C9orf3, ONPEP, Aminopeptidase O, FLJ14675) - 123375 from USBiological Life Science

Host Mouse
Clonality Polyclonal

Anti -AOPEP, NT (AOPEP, C9orf3, ONPEP, Aminopeptidase O) - 031935 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -AOPEP, NT (AOPEP, C9orf3, ONPEP, Aminopeptidase O) (AP) - 031935-AP from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -AOPEP, NT (AOPEP, C9orf3, ONPEP, Aminopeptidase O) (APC) - 031935-APC from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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