C9orf3

Gene Symbol C9orf3
Entrez Gene 84909
Alt Symbol AOPEP, AP-O, APO, C90RF3, ONPEP
Species Human
Gene Type protein-coding
Description chromosome 9 open reading frame 3
Other Description aminopeptidase O
Swissprots Q96SS1 Q5T9B4 Q96M23 Q5T9B1 Q8WUL6 Q5T9B3 Q8N6M6
Accessions EAW92618 EAW92619 EAW92620 EAW92621 EAW92622 EAW92623 Q8N6M6 AF043896 AF043897 AI982632 AJ560639 CAD90259 AK027581 BAB55210 AK057450 BAB71491 AK098242 AK130021 AK296699 BAG59293 AK296782 BAG59360 AK298959 BAG61055 AK300486 BAG62201 AL137535 BC020194 AAH20194 BC029616 AAH29616 BC042892 BP274281 BQ448239 BX099259 BX648970 DA222106 DA521148 XM_005252284 XP_005252341 XM_006717306 XP_006717369 XM_011519119 XP_011517421 XM_011519120 XP_011517422 XM_011519121 XP_011517423 XM_011519122 XP_011517424 XM_011519123 XP_011517425 XM_011519124 XP_011517426 XM_011519125 XP_011517427 XM_011519126 XP_011517428 XM_011519127 XP_011517429 XM_011519128 XP_011517430 XM_011519129 XP_011517431 XM_011519130 XP_011517432 XM_011519131 XP_011517433 XM_011519132 XP_011517434 XM_011519133 XP_011517435 XM_011519134 XP_011517436 XM_011519135 XP_011517437 XR_929852 XR_929853 XR_929854 XR_929855 XR_929856 XR_929857 XR_929858 NM_001193329 NP_001180258 NM_001193331 NP_001180260 NM_032823 NP_116212 NM_001193330
Function Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart. {ECO:0000269|PubMed:15687497}.
Subcellular Location Cytoplasm {ECO:0000305}.
Tissue Specificity Predominantly expressed in pancreas, placenta, liver, testis and heart. Expressed at lower level in brain, lung and kidney. {ECO:0000269|PubMed:15687497}.

APO CRISPR/Cas9 KO Plasmid (h) - sc-413725 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APO HDR Plasmid (h) - sc-413725-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APO Double Nickase Plasmid (h) - sc-413725-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APO Double Nickase Plasmid (h2) - sc-413725-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APO CRISPR Activation Plasmid (h) - sc-413725-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APO CRISPR Activation Plasmid (h2) - sc-413725-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APO Lentiviral Activation Particles (h) - sc-413725-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APO Lentiviral Activation Particles (h2) - sc-413725-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APO siRNA (h) - sc-92896 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APO shRNA Plasmid (h) - sc-92896-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APO shRNA (h) Lentiviral Particles - sc-92896-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Aminopeptidase O/ONPEP RNAi - H00084909-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU141041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5202 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

AOPEP siRNA (Human) - CRJ3684 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AOPEP - MBS8219513 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C9orf3 (NM_032823.5) - SHH252909 from Creative biogene

Category siRNA
Species Reactivities Human

AOPEP shRNA Plasmid (Human) - CHJ3684 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

C9ORF3 miRNA 3'UTR clone - MiUTR3H-14252 from Creative biogene

Species Reactivities Human
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