Gene Symbol | AQP1 |
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Entrez Gene | 358 |
Alt Symbol | AQP-CHIP, CHIP28, CO |
Species | Human |
Gene Type | protein-coding |
Description | aquaporin 1 (Colton blood group) |
Other Description | aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group)|aquaporin-1|aquaporin-CHIP|channel-like integral membrane protein, 28-kDa|urine water channel|water channel protein for red blood cells and kidney proximal tubule |
Swissprots | Q8TDC1 F5GY19 B5BU39 E9PC21 Q8TBI5 E7EM69 P29972 |
Accessions | AAC16481 AAC23788 AAL87136 AAX24129 CAC84072 CAQ51480 CBG76070 EAL24446 EAW93971 EAW93972 P29972 AB451275 BAG70089 AB451402 BAG70216 AK298091 BAG60376 AK298313 BAG60567 AK300995 BAG62614 AK301351 BAG62897 AK304684 BAG65455 AK309608 AK309688 AK309691 AK312656 BAG35539 AU122128 AY312580 AAR16185 AY312581 AAR16186 BC022486 AAH22486 BC141905 BI837828 DA197236 DA712111 DQ892366 ABM83292 DQ895575 ABM86501 M77829 AAA58425 S73482 AAB31193 U41517 AAC50648 U41518 AAC50649 NM_001185060 NP_001171989 NM_001185061 NP_001171990 NM_001185062 NP_001171991 NM_198098 NP_932766 NM_000385 |
Function | Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. {ECO:0000269|PubMed:1373524}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:23219802}; Multi-pass membrane protein {ECO:0000269|PubMed:23219802}. |
Tissue Specificity | Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver. {ECO:0000269|PubMed:23219802}. |
Top Pathways | Proximal tubule bicarbonate reclamation, Bile secretion |
Aquaporin 1 peptide - ab25381 from Abcam
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Human Aquaporin 1 full length protein - ab114210 from Abcam
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Human Aquaporin 1 peptide - ab97414 from Abcam
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AQP1 / Aquaporin 1 Antibody Blocking Peptide - LS-E5390 from LifeSpan Bioscience
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Recombinant Human Aquaporin 1/AQP1 Protein - H00000358-P01 from Novus Biologicals
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AQP1-Antibody-C-term-Blocking-Peptide - BP17893b from Abgent, a WuXi AppTec company
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Recombinant human Aquaporin-1 protein (OPCA01091) - OPCA01091 from Aviva Systems Biology
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Aquaporin 1 Proteins - orb244028 from Biorbyt
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Aquaporin 1 Proteins - orb245638 from Biorbyt
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Human AQP1 Protein - abx065446 from Abbexa
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Aquaporin-1 - H00000358-P01-10 from Acris Antibodies
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Aquaporin-1 - H00000358-P01-25 from Acris Antibodies
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Aquaporin-1 / AQP1 control peptide - AP09887CP-N from Acris Antibodies
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Aquaporin 1, Colton Blood Group (AQP1), Human - 20-6845 from ARP American Research Products
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AQP1 fusion protein - Ag14093 from Proteintech Group
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Recombinant Human AQP1, GST-tagged - AQP1-9779H from Creative Biomart
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Recombinant Human AQP1, His-tagged, GST-tagged - AQP1-3592H from Creative Biomart
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Recombinant Aquaporin 1, Colton Blood Group (AQP1) - RPA579Hu01 from Uscn Life Science Inc.
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Aquaporin 1 Blocking Peptide - CBP3132 from Cohesion Biosciences
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AQP1 (N134) Peptide - BS3709P from Bioworld Technology
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Recombinant Aquaporin 1, Colton Blood Group (AQP1) - RPA579Hu01 from Cloud-clone
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Recombinant human Aquaporin-1 - CSB-YP001957HU CSB-BP001957HU CSB-MP001957HU from Cusabio
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Recombinant human Aquaporin-1 protein - CSB-EP160844h(A4) CSB-BP160844h(A4) CSB-MP160844h(A4) from Cusabio
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Recombinant human Aquaporin-1 - CSB-EP001957HU from Cusabio
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Recombinant Human Aquaporin-1(AQP1),partial - CSB-RP160844h(A4) from Cusabio
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