AQP1

Gene Symbol AQP1
Entrez Gene 358
Alt Symbol AQP-CHIP, CHIP28, CO
Species Human
Gene Type protein-coding
Description aquaporin 1 (Colton blood group)
Other Description aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group)|aquaporin-1|aquaporin-CHIP|channel-like integral membrane protein, 28-kDa|urine water channel|water channel protein for red blood cells and kidney proximal tubule
Swissprots Q8TDC1 F5GY19 B5BU39 E9PC21 Q8TBI5 E7EM69 P29972
Accessions AAC16481 AAC23788 AAL87136 AAX24129 CAC84072 CAQ51480 CBG76070 EAL24446 EAW93971 EAW93972 P29972 AB451275 BAG70089 AB451402 BAG70216 AK298091 BAG60376 AK298313 BAG60567 AK300995 BAG62614 AK301351 BAG62897 AK304684 BAG65455 AK309608 AK309688 AK309691 AK312656 BAG35539 AU122128 AY312580 AAR16185 AY312581 AAR16186 BC022486 AAH22486 BC141905 BI837828 DA197236 DA712111 DQ892366 ABM83292 DQ895575 ABM86501 M77829 AAA58425 S73482 AAB31193 U41517 AAC50648 U41518 AAC50649 NM_001185060 NP_001171989 NM_001185061 NP_001171990 NM_001185062 NP_001171991 NM_198098 NP_932766 NM_000385
Function Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. {ECO:0000269|PubMed:1373524}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:23219802}; Multi-pass membrane protein {ECO:0000269|PubMed:23219802}.
Tissue Specificity Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver. {ECO:0000269|PubMed:23219802}.
Top Pathways Proximal tubule bicarbonate reclamation, Bile secretion

AQP1 (L-19) - sc-9878 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AQP1 (L-19): sc-9878. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing membrane and cytoplasmic staining of cells in glomeruli and cells in tubules.

AQP1 (T-13) - sc-34008 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AQP1 (T-13): sc-34008. Western blot analysis of human recombinant AQP1 fusion protein.

AQP1 (A-11) - sc-55466 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AQP1 (A-11): sc-55466. Western blot analysis of AQP1 expression in mouse kidney (A) and rat kidney (B) tissue extracts.

AQP1 (H-55) - sc-20810 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AQP1 (H-55): sc-20810. Immunofluorescence staining of methanol-fixed KNRK cells showing membrane localization.

AQP1 (1) - sc-32738 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AQP1 (1): sc-32738. Immunoperoxidase staining of formalin fixed, paraffin-embedded rat brain tissue showing membrane localization.

AQP1 (B-11) - sc-25287 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AQP1 (B-11): sc-25287. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse kidney tissue showing membrane localization.

AQP1 (C-20) - sc-9879 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

AQP1 (P-16) - sc-34009 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AQP1 (P-16): sc-34009. Western blot analysis of human recombinant AQP1 fusion protein.

AQP1 (1/22) - sc-32737 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AQP1 (1/22): sc-32737. Western blot analysis of AQP1 expression in mouse kidney (A) and rat kidney (B) tissue extracts.

Anti-Aquaporin 1 antibody - ab15080 from Abcam

Prices $400.00
Sizes 25 µl
Host Rabbit
Clonality Polyclonal
ab15080 staining Aquaporin1 in porcine jejunum by immunohistochemistry (Frozen sections). Tissue underwent fixation in paraformaldehyde without undergoing permeabilization and blocking steps. The primary antibody diluted 1/500 and incubated with sample for 24 hours. A Texas Red® conjugated goat polyclonal IgG whole molecule to rabbit, diluted 1/400 was used as the secondary.See Abreview

Anti-Aquaporin 1 antibody - ab65837 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Aquaporin 1 antibody (ab65837) at 2 µg/ml + rat kidney lysate

Anti-Aquaporin 1 antibody - ab125041 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab125041, at 1/200, staining Aquaporin 1 in Rat kidney tissue by Immunofluorescence.

Anti-Aquaporin 1 antibody - ab87845 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Aquaporin 1 antibody (ab87845) at 1 µg/mlLane 1 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 2 : Pancreas (Human) Tissue Lysate - adult normal tissue (ab29816)Lane 3 : Skeletal Muscle (Human) Tissue Lysate - adult normal tissue (ab29330)Lane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLane 5 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Aquaporin 1 antibody [1/22] - ab9566 from Abcam

Prices $392.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1/22
Immunohistochemical staining of aquaporin 1 in rat brain.

Anti-Aquaporin 1 antibody [1/A5F6] - ab11023 from Abcam

Prices $373.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1/A5F6

Anti-Aquaporin 1 antibody [10C11] - ab117970 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10C11
All lanes : Anti-Aquaporin 1 antibody [10C11] (ab117970) at 1/2000 dilutionLane 1 : HEK293T cell lysate, transfected with pCMV6-ENTRY control Lane 2 : HEK293T cell lysate, transfected with pCMV6-ENTRY Aquaporin 1Lysates/proteins at 5 µg per lane.

Anti-Aquaporin 1 antibody [7D11] - ab11025 from Abcam

Prices $373.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 7D11

Anti-Aquaporin 1 antibody [EPR11588(B)] - ab168387 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11588(B)
ab168387 showing +ve staining in Human normal spleen.

Anti-Aquaporin 1 antibody - N-terminal - ab189291 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue, labeling Aquaporin 1 using ab189291 at 10 µg/ml.

Anti-AQP1 / Aquaporin 1 Antibody (aa249-269) - LS-C3793 from LifeSpan Bioscience

Prices $725.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-AQP1 / Aquaporin 1 Antibody (C-Terminus) - LS-C3795 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-AQP1 / Aquaporin 1 Antibody (aa243-261) - LS-C3815 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-AQP1 / Aquaporin 1 Antibody (aa243-261, Biotin) - LS-C3816 from LifeSpan Bioscience

Prices $590.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-AQP1 / Aquaporin 1 Antibody (aa249-269) - LS-C69211 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-AQP1 / Aquaporin 1 Antibody (C-Terminus) - LS-C121388 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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