| Gene Symbol |
DOK6
|
| Entrez Gene |
220164
|
| Alt Symbol |
DOK5L, HsT3226
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
docking protein 6
|
| Other Description |
downstream of tyrosine kinase 6
|
| Swissprots |
Q8WUZ8 A6NNG3 Q6PKX4 Q96LU2 Q96HI2 Q4V9S3
|
| Accessions |
EAW66514 Q6PKX4 AK057795 BAB71577 AL512695 AY599248 AAT09770 BC008583 AAH08583 BC019045 AAH19045 BC096744 AAH96744 BX280184 DB480182 XM_011525873 XP_011524175 XM_011525874 XP_011524176 XM_011525875 XP_011524177 XM_011525876 XP_011524178 NM_152721 NP_689934
|
| Function |
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret- mediated neurite growth. May have a role in brain development and/or maintenance. {ECO:0000269|PubMed:15286081}.
|
| Tissue Specificity |
Highly expressed in fetal and adult brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis. {ECO:0000269|PubMed:15286081}.
|
![Western Blot: DOK6 Overexpression Lysate (Adult Normal) [NBL1-09981] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DOK6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3304_DOK6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09981-img0002.jpg)