EXOC7

Gene Symbol EXOC7
Entrez Gene 23265
Alt Symbol 2-5-3p, EX070, EXO70, EXOC1, Exo70p, YJL085W
Species Human
Gene Type protein-coding
Description exocyst complex component 7
Other Description exocyst complex component Exo70
Swissprots Q8ND93 Q9H8C3 Q9H9X3 Q8WV91 Q9UPT5 B8XXP2 B5MC69 Q9HA32 Q96FF0
Accessions AAC25180 EAW89367 EAW89368 EAW89369 EAW89370 EAW89371 EAW89372 EAW89373 EAW89374 Q9UPT5 AA215645 AB028990 BAA83019 AI565863 AI653861 AK000718 AK022397 BAB14026 AK022552 BAB14095 AK023832 BAB14694 AK024769 AK098284 AK128278 AK295871 BAG58669 AL162005 AL834324 CAD38992 AY869728 AAW65095 BC011045 AAH11045 BC015165 AAH15165 BC018466 AAH18466 BC029432 BX647763 CAH56185 BX648435 CB989148 DA224278 DC319923 FJ457119 ACK36853 FJ457120 ACK36854 HY020675 XM_006721786 XP_006721849 XM_006721787 XP_006721850 XM_006721788 XP_006721851 XM_006721789 XP_006721852 XM_011524571 XP_011522873 XM_011524572 XP_011522874 NM_001013839 NP_001013861 NM_001145297 NP_001138769 NM_001145298 NP_001138770 NM_001145299 NP_001138771 NM_001282313 NP_001269242 NM_001282314 NP_001269243 NM_015219 NP_056034
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Translocates, as a preformed complex with SEC6 and SEC8, to the plasma membrane in response to insulin through the activation of ARHQ. {ECO:0000250}.
Top Pathways Insulin signaling pathway

Exo70 (D-16) - sc-167766 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Exo70 (D-16): sc-167766. Western blot analysis of Exo70 expression in Jurkat whole cell lysate.

Exo70 (D-6) - sc-365825 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Exo70 (D-6): sc-365825. Western blot analysis of Exo70 expression in non-transfected: sc-117752 (A) and mouse Exo70 transfected: sc-125314 (B) 293T whole cell lysates.

Exo70 (H-9) - sc-514257 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Exo70 (H-9): sc-514257. Western blot analysis of Exo70 expression in non-transfected 293T: sc-117752 (A), mouse Exo70 transfected 293T: sc-125314 (B), HeLa (C), Jurkat (D), MOLT-4 (E) and Hep G2 (F) whole cell lysates.

Exo70 (H-300) - sc-135082 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Exo70 (K-13) - sc-167767 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Exo70 (K-13): sc-167767. Western blot analysis of Exo70 expression in rat brain tissue extract.

Exo70 (ZZ-7) - sc-100733 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Exo70 (ZZ-7): sc-100733. Western blot analysis of Exo70 expression in HeLa whole cell lysate.

Anti-EXOC7 antibody - ab57402 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
EXOC7 antibody (ab57402) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.

Anti-EXOC7 antibody - ab95981 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-EXOC7 antibody (ab95981) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-EXOC7 Antibody (aa586-685, Azide-free) - LS-C327344 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-EXOC7 Antibody (aa493-735) - LS-C186251 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: Molt-4 . 7.5% SDS PAGE. EXOC7 antibody diluted at 1:1000.

Anti-EXOC7 Antibody (Internal) - LS-C345639 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of EXOC7 Antibody with human PANC1 Whole Cell lysate.

Anti-EXOC7 Antibody (aa1-50) - LS-C290049 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse Exo70 by Western Blot (h and m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug), Jurkat (J; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Exo70 antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. Exo70 was also immunoprecipitated by rabbit anti-Exo70 antibody BL12126, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

Anti-EXOC7 Antibody (aa74-335) - LS-C186247 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of paraformaldehyde-fixed A431 using EXOC7 antibody at 1:200 dilution.

Anti-EXOC7 Antibody (clone 1D4) - LS-C133704 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D4
Immunoperoxidase of monoclonal antibody to EXOC7 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]

Anti-EXOC7 Antibody (aa453-464) IHC-plus™ - LS-B2297 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-EXOC7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2297 concentration 5 ug/ml.

EXOC7 Antibody - NBP1-84767 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EXOC7 Antibody (1D4) - H00023265-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D4
Western Blot: EXOC7 Antibody (1D4) [H00023265-M01] - EXOC7 monoclonal antibody (M01), clone 1D4 Analysis of EXOC7 expression in HeLa.

EXOC7 Antibody - NB100-94901 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: EXOC7 Antibody [NB100-94901] - (0.5ug/ml) staining of Human Lung lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

EXOC7 Antibody - NBP1-84766 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: EXOC7 Antibody [NBP1-84766] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

EXOC7 Antibody - NBP1-33333 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EXOC7 Antibody - H00023265-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Monoclonal Anti-EXOC7 antibody produced in mouse - WH0023265M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D4
<B>Immunoblotting</B><BR/>Monoclonal Anti-EXOC7, <B>Cat. No. WH0023265M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~83.3 kDa using HeLa lysate.

Anti-EXOC7 antibody produced in rabbit - HPA022842 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-EXOC7: <B>Cat. No. HPA022842</B>: Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Anti-EXOC7 antibody produced in goat - SAB2500372 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-EXOC7: <B>Cat. No. SAB2500372</B>: (0.5 μg/mL) staining of Human Lung lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Monoclonal Anti-EXOC7, (C-terminal) antibody produced in mouse - SAB1404961 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B7
<B>Immunoblotting</B><BR/>Monoclonal Anti-EXOC7: <B>Cat. No. SAB1404961</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~83.4 kDa using HeLa lysate.
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