OTUB2

Gene Symbol OTUB2
Entrez Gene 78990
Alt Symbol C14orf137, OTB2, OTU2
Species Human
Gene Type protein-coding
Description OTU deubiquitinase, ubiquitin aldehyde binding 2
Other Description OTU domain, ubiquitin aldehyde binding 2|OTU domain-containing ubiquitin aldehyde-binding protein 2|deubiquitinating enzyme OTUB2|otubain-2|ubiquitin thioesterase OTUB2|ubiquitin-specific protease otubain 2|ubiquitin-specific-processing protease OTUB2
Swissprots Q9H6T1 Q96DC9 Q6IA10
Accessions EAW81548 EAW81549 Q96DC9 AF318378 AAL55885 AI018242 AK025569 BAB15172 AY177201 AAO27703 BC000208 AAH00208 BC009615 AAH09615 BC068058 AAH68058 BG423958 CR457345 CAG33626 HQ447541 ADQ32027 XM_005268055 XP_005268112 XM_006725171 XP_006725234 XM_011537147 XP_011535449 XM_011537148 XP_011535450 XM_011537149 XP_011535451 XM_011546664 XP_011544966 XM_011546665 XP_011544967 XM_011546666 XP_011544968 NM_023112 NP_075601
Function Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'- linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:12704427, ECO:0000269|PubMed:18954305, ECO:0000269|PubMed:23827681}.
Tissue Specificity Widely expressed. Expressed at higher level in brain. {ECO:0000269|PubMed:12704427}.

OTUB2 CRISPR/Cas9 KO Plasmid (h) - sc-413099 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUB2 HDR Plasmid (h) - sc-413099-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUB2 Double Nickase Plasmid (h) - sc-413099-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUB2 Double Nickase Plasmid (h2) - sc-413099-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUB2 CRISPR Activation Plasmid (h) - sc-413099-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUB2 CRISPR Activation Plasmid (h2) - sc-413099-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUB2 Lentiviral Activation Particles (h) - sc-413099-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUB2 Lentiviral Activation Particles (h2) - sc-413099-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUB2 siRNA (h) - sc-76016 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OTUB2 shRNA Plasmid (h) - sc-76016-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OTUB2 shRNA (h) Lentiviral Particles - sc-76016-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Otubain-2 RNAi - H00078990-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU054501 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16195 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16195 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

OTUB2 siRNA (Human) - CRJ2236 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human OTUB2 (NM_023112.3) - SHH369088 from Creative biogene

Category siRNA
Species Reactivities Human

Human OTUB2 siRNA - orb272737 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

OTUB2 shRNA Plasmid (Human) - CHJ2236 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

OTUB2 miRNA 3'UTR clone - MiUTR1H-07416 from Creative biogene

Species Reactivities Human
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