Gene Symbol | IL12RB1 |
---|---|
Entrez Gene | 3594 |
Alt Symbol | CD212, IL-12R-BETA1, IL12RB, IMD30 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 12 receptor, beta 1 |
Other Description | IL-12 receptor beta component|IL-12 receptor subunit beta-1|IL-12R subunit beta-1|cluster of differentiation 212|interleukin-12 receptor beta-1 chain|interleukin-12 receptor subunit beta-1 |
Swissprots | B2RPF1 P42701 Q8N6Q7 B7ZKK3 A8K308 |
Accessions | AAV28734 CAC10446 EAW84653 EAW84654 EAW84655 EAW84656 P42701 AI637915 AK225919 AK290423 BAF83112 BC029121 AAH29121 BC137404 AAI37405 BC137406 AAI37407 BX647221 DA008204 EU832463 ACE87635 EU832511 ACE87683 EU832545 ACE86947 EU832592 ACE86994 JF432889 ADZ16106 U03187 AAA21340 XM_006722741 XP_006722804 XM_011527966 XP_011526268 XM_011527967 XP_011526269 XM_011527968 XP_011526270 XM_011527969 XP_011526271 XM_011527970 XP_011526272 XM_011527971 XP_011526273 XM_011527972 XP_011526274 XM_011527973 XP_011526275 XM_011527974 XP_011526276 XM_011527975 XP_011526277 XM_011527976 XP_011526278 XM_011527977 XP_011526279 NM_001290023 NP_001276952 NM_001290024 NP_001276953 NM_005535 NP_005526 NM_153701 NP_714912 |
Function | Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. {ECO:0000269|PubMed:12023369}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD) |
IL-12Rβ1 (A-10) - sc-166776 from Santa Cruz Biotechnology
|
||||||||||
IL-12Rβ1 (E-6) - sc-166805 from Santa Cruz Biotechnology
|
||||||||||
IL-12Rβ1 (DU-1) - sc-13511 from Santa Cruz Biotechnology
|
||||||||||
IL-12Rβ1 (C-20) - sc-658 from Santa Cruz Biotechnology
|
||||||||||
IL-12Rβ1 (H-300) - sc-25479 from Santa Cruz Biotechnology
|
||||||||||
IL-12Rβ1 (L-20) - sc-18644 from Santa Cruz Biotechnology
|
||||||||||
Anti-IL12RB1 antibody - ab197685 from Abcam
|
||||||||||
Anti-IL12RB1 antibody - ab96517 from Abcam
|
||||||||||
Anti-IL12RB1 antibody - ab10781 from Abcam
|
||||||||||
Anti-IL12RB1 antibody [MM0363-7V24] - ab89890 from Abcam
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (aa37-234, FITC) - LS-C304965 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (aa429-603, FITC) - LS-C304076 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (aa37-234, Biotin) - LS-C300781 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (clone TOS) - LS-C179386 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody - LS-C310735 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody - LS-C310734 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (aa451-463) - LS-C113006 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (aa429-603) - LS-C294827 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (aa57-488) - LS-C185574 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (clone TOS, PE) - LS-C179387 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody - LS-C335191 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (Extracellular Domain, CF) - LS-C130259 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (Extracellular Domain, PE) - LS-C130260 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (aa37-234) - LS-C294825 from LifeSpan Bioscience
|
||||||||||
Anti-IL12RB1 / CD212 Antibody (aa429-603, Biotin) - LS-C299850 from LifeSpan Bioscience
|