F3

Gene Symbol F3
Entrez Gene 2152
Alt Symbol CD142, TF, TFA
Species Human
Gene Type protein-coding
Description coagulation factor III (thromboplastin, tissue factor)
Other Description tissue factor
Swissprots Q6FHG2 Q86WH4 P13726 D3DT47
Accessions AAA61152 AAN01236 CAA01438 EAW73043 EAW73044 EAW73045 P13726 AF487337 AAO61150 AF497569 AAO61151 AF497570 AAO61152 AF497571 AAO61153 AK310918 AK312638 BAG35522 AY940729 AY940730 AY940731 BC011029 AAH11029 BM769013 BM981095 BT019808 AAV38611 CR541792 CAG46591 DB203987 DB499288 DQ892755 ABM83681 J02931 AAA61150 M16553 AAA61151 M27436 AAA36734 X07680 CAA30527 NM_001178096 NP_001171567 NM_001993 NP_001984
Function Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. {ECO:0000269|PubMed:12652293}.
Subcellular Location Isoform 1: Membrane; Single-pass type I membrane protein.
Tissue Specificity Lung, placenta and pancreas. {ECO:0000269|PubMed:12652293}.
Top Pathways Complement and coagulation cascades

TF CRISPR/Cas9 KO Plasmid (h) - sc-401060 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TF HDR Plasmid (h) - sc-401060-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TF Double Nickase Plasmid (h) - sc-401060-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TF Double Nickase Plasmid (h2) - sc-401060-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TF CRISPR Activation Plasmid (h) - sc-401060-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TF CRISPR Activation Plasmid (h2) - sc-401060-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TF Lentiviral Activation Particles (h) - sc-401060-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TF Lentiviral Activation Particles (h2) - sc-401060-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TF siRNA (h) - sc-44984 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TF shRNA Plasmid (h) - sc-44984-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TF shRNA (h) Lentiviral Particles - sc-44984-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU076311 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8071 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8071 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08689 from Sigma-Aldrich

Category miRNA

F3 siRNA (Human) - CRH1496 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD142 - MBS826803 from MyBioSource

Prices $255.00
Sizes 5 od
Species Reactivities Human

F3 - MBS8218366 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

F3 shRNA Plasmid (Human) - CHH1496 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

F3 miRNA 3'UTR clone - MiUTR1H-03364 from Creative biogene

Species Reactivities Human

F3 miRNA 3'UTR clone - MiUTR1H-03365 from Creative biogene

Species Reactivities Human
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