MUTYH

Gene Symbol MUTYH
Entrez Gene 4595
Alt Symbol MYH
Species Human
Gene Type protein-coding
Description mutY homolog
Other Description A/G-specific adenine DNA glycosylase
Swissprots Q9UBS7 Q9UIF5 D3DPZ4 Q9UBP2 Q15830 Q9UIF7 Q9UIF6 Q9UIF4
Accessions AAC50618 AAM78555 ADP90934 ADP90935 ADP90936 ADP90937 ADP90938 ADP90939 ADP90940 ADP90941 ADP90942 ADP90943 ADP90944 ADP90945 ADP90946 ADP90947 ADP90948 ADP90949 ADP90950 ADP90951 ADP90952 ADP90953 ADP90954 ADP90955 ADP90956 ADP90957 ADP90958 ADP90959 ADP90960 ADP90961 ADP90962 ADP90963 ADP90964 ADP90965 ADP90966 ADP90967 ADP90968 ADP90969 ADP90970 ADP90971 ADP90972 ADP90973 ADP90974 ADP90975 ADP90976 ADP90977 ADP90978 ADP90979 ADP90980 ADP90981 ADP90982 ADP90983 ADP90984 ADP90985 ADP90986 ADP90987 ADP90988 ADP90989 ADP90990 ADP90991 ADP90992 ADP90993 ADP90994 ADP90995 ADP90996 ADP90997 ADP90998 ADP90999 ADP91000 ADP91001 ADP91002 ADP91003 ADP91004 ADP91005 ADP91006 ADP91007 ADP91008 ADP91009 ADP91010 ADP91011 ADP91012 ADP91013 ADP91014 ADP91015 ADP91016 ADP91017 ADP91018 ADP91019 ADP91020 ADP91021 ADP91022 ADP91023 ADP91024 ADP91025 ADP91026 ADP91027 ADP91028 ADP91029 ADP91030 ADP91031 ADP91032 ADP91033 ADP91034 ADP91035 ADP91036 ADP91037 ADP91038 ADP91039 ADP91040 ADP91041 ADP91042 ADP91043 ADP91044 ADP91045 ADP91046 ADP91047 ADP91048 ADP91049 ADP91050 ADP91051 ADP91052 ADP91053 ADP91054 ADP91055 ADP91056 ADP91057 ADP91058 ADP91059 ADP91060 ADP91061 ADP91062 ADP91063 ADP91064 ADP91065 ADP91066 ADP91067 ADP91068 ADP91069 ADP91070 ADP91071 ADP91072 ADP91073 ADP91074 ADP91075 ADP91076 ADP91077 ADP91078 ADP91079 ADP91080 ADP91081 ADP91082 ADP91083 ADP91084 ADP91085 ADP91086 ADP91087 ADP91088 ADP91089 ADP91090 ADP91091 ADP91092 ADP91093 ADP91094 ADP91095 ADP91096 ADP91097 ADP91098 ADP91099 ADP91100 ADP91101 ADP91102 ADP91103 ADP91104 ADP91105 ADP91106 ADP91107 ADP91108 ADP91109 ADP91110 ADP91111 ADP91112 ADP91113 ADP91114 ADP91115 ADP91116 ADP91117 ADP91118 ADP91119 ADP91120 ADP91121 ADP91122 ADP91123 ADP91124 ADP91125 ADP91126 ADP91127 ADP91128 ADP91129 ADP91130 ADP91131 ADP91132 ADP91133 BAB86886 EAX06991 EAX06992 EAX06993 EAX06994 EAX06995 EAX06996 EAX06997 EAX06998 EAX06999 EAX07000 EAX07001 Q9UIF7 AB025227 BAA84104 AB032920 BAA89336 AB032921 BAA89337 AB032922 BAA89338 AB032923 BAA89339 AB032924 BAA89340 AB032925 BAA89341 AB032926 BAA89342 AB032927 BAA89343 AB032928 BAA89344 AB032929 BAA89345 AK293830 BAG57233 AL560568 BC003178 AAH03178 BI818560 BM926983 CN413115 HY094590 XM_011541497 XP_011539799 XM_011541498 XP_011539800 XM_011541499 XP_011539801 XM_011541500 XP_011539802 XM_011541501 XP_011539803 XM_011541502 XP_011539804 XM_011541503 XP_011539805 XM_011541504 XP_011539806 XM_011541505 XP_011539807 XM_011541506 XP_011539808 XM_011541507 XP_011539809 XM_011541508 XP_011539810 XR_946658 NM_001048171 NP_001041636 NM_001048172 NP_001041637 NM_001048173 NP_001041638 NM_001048174 NP_001041639 NM_001128425 NP_001121897 NM_001293190 NP_001280119 NM_001293191 NP_001280120 NM_001293192 NP_001280121 NM_001293195 NP_001280124 NM_001293196 NP_001280125 NM_012222 NP_036354
Function Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2- OH-A DNA glycosylase activities. {ECO:0000269|PubMed:10684930}.
Subcellular Location Nucleus.
Top Pathways Base excision repair

MYH Antibody - 5159 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using MYH Antibody.

MYH (D13D4) Rabbit mAb - 6248 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D13D4
Western blot analysis of extracts from various cell lines using MYH (D13D4) Rabbit mAb.

MUTYH (C-6) - sc-374571 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MUTYH (C-6): sc-374571. Western blot analysis of MUTYH expression in Jurkat (A) and HL-60 (B) whole cell lysates.

MUTYH (H-44) - sc-99211 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MUTYH (C-16) - sc-25171 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MUTYH (N-15) - sc-25169 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MUTYH (N-15): sc-25169. Western blot analysis of MUTYH expression in Jurkat (A), K-562 (B), HL-60 (C) and SW480 (D) nuclear extracts.

MUTYH (C-14) - sc-30630 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MYH (TH81) - sc-101334 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-MYH antibody - ab55551 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MYH antibody - ab182759 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling MYH with ab182759 at 1/60 dilution (left panel). Right panel is treated with the immunogen.

Anti-MYH antibody - ab58572 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-MYH antibody (ab58572) at 0.1 µg/ml + Human Bone Marrow lysate at 35 µg

Anti-MYH antibody - ab138101 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MYH antibody (ab138101) at 1/500 dilution + HUVEC cell lysate at 30 µg

Anti-MYH antibody - ab13698 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MYH antibody [EP4669] - ab124914 from Abcam

Host Rabbit
Clonality Monoclonal
Clone EP4669
All lanes : Anti-MYH antibody [EP4669] (ab124914) at 1/1000 dilutionLane 1 : K-562 cell lysateLane 2 : Jurkat cell lysateLane 3 : HepG2 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-MUTYH / MYH Antibody (C-Terminus) - LS-C204259 from LifeSpan Bioscience

Prices $355.00
Sizes 600 µg
Host Goat
Clonality Polyclonal
Western blot. Anti-Mutyh antibody at 1:1000 dilution. Recombinant protein at 50 ng and 293HEK transfected lysate at 100 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.

Anti-MUTYH / MYH Antibody (aa151-200) - LS-C119579 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using MUTYH Antibody. The picture on the right is treated with the synthesized peptide.

Anti-MUTYH / MYH Antibody - LS-C331584 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using MUTYH antibody.

Anti-MUTYH / MYH Antibody (Tyr176) - LS-C177045 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of MYH (Y176) pAb in paraffin-embedded human colon carcinoma tissue.

Anti-MUTYH / MYH Antibody (aa127-176) - LS-C200241 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HUVEC cells using MUTYH antibody.

Anti-MUTYH / MYH Antibody (aa341-367) - LS-C164686 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Confocal immunofluorescent of MUTYH Antibody with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Anti-MUTYH / MYH Antibody (aa531-546) IHC-plus™ - LS-B1974 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MUTYH antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1974 concentration 10 ug/ml.

Anti-MUTYH / MYH Antibody (clone 4D10) - LS-C197721 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4D10
Western Blot analysis of MUTYH expression in transfected 293T cell line by MUTYH monoclonal antibody (M01), clone 4D10.Lane 1: MUTYH transfected lysate(59.1 KDa).Lane 2: Non-transfected lysate.

Anti-MUTYH / MYH Antibody (N-Terminus) - LS-C25689 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-MUTYH / MYH Antibody (C-Terminus) - LS-C25691 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-MUTYH Antibody (Internal, clone EP4669) - LS-C138894 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP4669
Western blot analysis on (A) K562, (B) Jurkat, and (C) HepG2 cell lysates using anti-MYH antibody.
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