| Gene Symbol | CANX |
|---|---|
| Entrez Gene | 403908 |
| Alt Symbol | PP90 |
| Species | Dog |
| Gene Type | protein-coding |
| Description | calnexin |
| Other Description | - |
| Swissprots | P24643 P79140 |
| Accessions | P24643 X53616 CAA37678 NM_001003232 NP_001003232 |
| Function | Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse (By similarity). {ECO:0000250}. |
| Subcellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum {ECO:0000250}. Melanosome {ECO:0000250}. Note=The palmitoylated form preferentially localizes to the perinuclear rough ER. {ECO:0000250}. |
| Top Pathways | Phagosome, Protein processing in endoplasmic reticulum, HTLV-I infection, Thyroid hormone synthesis, Antigen processing and presentation |
Recombinant Dog Calnexin - CANX-2072D from Creative Biomart
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Recombinant Dog Calnexin(CANX) ,partial - CSB-YP004485DO CSB-EP004485DO CSB-BP004485DO CSB-MP004485DO from Cusabio
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Calnexin (CANX), partial, Recombinant Protein - MBS950984 from MyBioSource
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Calnexin, Recombinant Protein - MBS7042386 from MyBioSource
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