Gene Symbol | CANX |
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Entrez Gene | 403908 |
Alt Symbol | PP90 |
Species | Dog |
Gene Type | protein-coding |
Description | calnexin |
Other Description | - |
Swissprots | P24643 P79140 |
Accessions | P24643 X53616 CAA37678 NM_001003232 NP_001003232 |
Function | Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum {ECO:0000250}. Melanosome {ECO:0000250}. Note=The palmitoylated form preferentially localizes to the perinuclear rough ER. {ECO:0000250}. |
Top Pathways | Phagosome, Protein processing in endoplasmic reticulum, HTLV-I infection, Thyroid hormone synthesis, Antigen processing and presentation |
Anti-Calnexin antibody - C-terminal - ab190092 from Abcam
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Anti-Calnexin antibody - C-terminal - ab192439 from Abcam
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Anti-Calnexin antibody - ER Marker - ab10286 from Abcam
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Anti-Calnexin antibody - ER Membrane Marker - ab22595 from Abcam
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Anti-Calnexin antibody - ER Membrane Marker - ab140818 from Abcam
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Calnexin Antibody - NB100-1965 from Novus Biologicals
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Calnexin Antibody - NBP1-97485 from Novus Biologicals
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Calnexin Antibody - NBP2-12724 from Novus Biologicals
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Calnexin Antibody [DyLight 550] - NB100-1965R from Novus Biologicals
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Calnexin Antibody [HRP] - NB100-1965H from Novus Biologicals
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Calnexin Antibody [DyLight 488] - NB100-1965G from Novus Biologicals
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Calnexin Antibody [DyLight 650] - NB100-1965C from Novus Biologicals
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Calnexin Antibody [Biotin] - NB100-1965B from Novus Biologicals
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Calnexin Antibody [FITC] - NB100-1965F from Novus Biologicals
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Calnexin Antibody [DyLight 405] - NB100-1965V from Novus Biologicals
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Calnexin Antibody [Alexa Fluor (R) 647] - NB100-1965AF647 from Novus Biologicals
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Calnexin Antibody [Alexa Fluor (R) 488] - NB100-1965AF488 from Novus Biologicals
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Calnexin Antibody [Alexa Fluor (R) 405] - NB100-1965AF405 from Novus Biologicals
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Calnexin Antibody [Alexa Fluor (R) 700] - NB100-1965AF700 from Novus Biologicals
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Anti-CANX antibody produced in rabbit - SAB5200097 from Sigma-Aldrich
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Anti-CANX antibody produced in rabbit - SAB5200084 from Sigma-Aldrich
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Anti-CANX antibody produced in rabbit - SAB5200081 from Sigma-Aldrich
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Calnexin-NT antibody (Streptavidin) - orb151570 from Biorbyt
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Anti -Calnexin - C1035-26B from USBiological Life Science
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Anti -Calnexin - C1035-26C from USBiological Life Science
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