| Gene Symbol |
GTF3A
|
| Entrez Gene |
2971
|
| Alt Symbol |
AP2, TFIIIA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
general transcription factor IIIA
|
| Other Description |
transcription factor IIIA
|
| Swissprots |
Q12963 B7ZBK5 Q13097 Q92664
|
| Accessions |
EAX08403 EAX08404 EAX08405 Q92664 AK057993 AW627732 BC143711 BP254755 D32257 BAA06988 U14134 AAA21873 U20272 AAA75623 NM_002097 NP_002088
|
| Function |
Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Ubiquitous.
|
![Western Blot: GTF3A Overexpression Lysate (Adult Normal) [NBP2-09779] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GTF3A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4428_GTF3A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-09779-img0001.jpg)