Gene Symbol | GTF3A |
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Entrez Gene | 2971 |
Alt Symbol | AP2, TFIIIA |
Species | Human |
Gene Type | protein-coding |
Description | general transcription factor IIIA |
Other Description | transcription factor IIIA |
Swissprots | Q12963 B7ZBK5 Q13097 Q92664 |
Accessions | EAX08403 EAX08404 EAX08405 Q92664 AK057993 AW627732 BC143711 BP254755 D32257 BAA06988 U14134 AAA21873 U20272 AAA75623 NM_002097 NP_002088 |
Function | Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes. |
Subcellular Location | Nucleus. |
Tissue Specificity | Ubiquitous. |
GTF3A CRISPR/Cas9 KO Plasmid (h) - sc-408737 from Santa Cruz Biotechnology
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GTF3A HDR Plasmid (h) - sc-408737-HDR from Santa Cruz Biotechnology
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GTF3A Double Nickase Plasmid (h) - sc-408737-NIC from Santa Cruz Biotechnology
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GTF3A Double Nickase Plasmid (h2) - sc-408737-NIC-2 from Santa Cruz Biotechnology
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GTF3A CRISPR Activation Plasmid (h) - sc-408737-ACT from Santa Cruz Biotechnology
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GTF3A CRISPR Activation Plasmid (h2) - sc-408737-ACT-2 from Santa Cruz Biotechnology
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GTF3A Lentiviral Activation Particles (h) - sc-408737-LAC from Santa Cruz Biotechnology
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GTF3A Lentiviral Activation Particles (h2) - sc-408737-LAC-2 from Santa Cruz Biotechnology
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GTF3A siRNA (h) - sc-75210 from Santa Cruz Biotechnology
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GTF3A shRNA Plasmid (h) - sc-75210-SH from Santa Cruz Biotechnology
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GTF3A shRNA (h) Lentiviral Particles - sc-75210-V from Santa Cruz Biotechnology
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GTF3A siRNA (h) - sc-105430 from Santa Cruz Biotechnology
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GTF3A shRNA Plasmid (h) - sc-105430-SH from Santa Cruz Biotechnology
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GTF3A shRNA (h) Lentiviral Particles - sc-105430-V from Santa Cruz Biotechnology
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GTF3A RNAi - H00002971-R01 from Novus Biologicals
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MISSION® esiRNA - EHU012831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9775 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9775 from Sigma-Aldrich
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GTF3A siRNA (Human) - CRH2012 from Cohesion Biosciences
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GTF3A - MBS8209830 from MyBioSource
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GTF3A shRNA Plasmid (Human) - CHH2012 from Cohesion Biosciences
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GTF3A miRNA 3'UTR clone - MiUTR3H-03687 from Creative biogene
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