Gene Symbol | APCDD1 |
---|---|
Entrez Gene | 147495 |
Alt Symbol | B7323, DRAPC1, FP7019, HHS, HTS, HYPT1 |
Species | Human |
Gene Type | protein-coding |
Description | adenomatosis polyposis coli down-regulated 1 |
Other Description | adenomatosis polyposis coli down-regulated 1 protein|hypoptrichosis simplex|protein APCDD1 |
Swissprots | B4DZT0 Q8J025 Q71M25 B4DUQ0 |
Accessions | CAF32599 EAX01585 EAX01586 Q8J025 AB056722 BAC15563 AB104887 BAC65165 AF461902 AAQ04816 AK300743 BAG62412 AK303076 BAG64192 AL110199 BC053324 AAH53324 XM_011525603 XP_011523905 NM_153000 NP_694545 |
Function | Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis. {ECO:0000269|PubMed:12384519, ECO:0000269|PubMed:20393562}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:20393562}; Single-pass type I membrane protein {ECO:0000269|PubMed:20393562}. |
Tissue Specificity | Abundantly expressed in heart, pancreas, prostate and ovary. Moderately expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. Abundantly expressed in both the epidermal and dermal compartments of the hair follicle. Present in scalp skin Highly expressed in the hair follicle dermal papilla, the matrix, and the hair shaft (at protein level). {ECO:0000269|PubMed:12384519, ECO:0000269|PubMed:20393562}. |
APCDD1 (D-17) - sc-84694 from Santa Cruz Biotechnology
|
||||||||
APCDD1 (E-17) - sc-84695 from Santa Cruz Biotechnology
|
||||||||
Anti-APCDD1 antibody - ab73063 from Abcam
|
||||||||
Anti-APCDD1 antibody - ab77476 from Abcam
|
||||||||
Anti-APCDD1 antibody - N-terminal - ab171851 from Abcam
|
||||||||
APCDD1 Antibody - NB110-92756 from Novus Biologicals
|
||||||||
APCDD1 Antibody - NBP1-88963 from Novus Biologicals
|
||||||||
APCDD1 Antibody - H00147495-B01P from Novus Biologicals
|
||||||||
APCDD1 Antibody [Biotin] - NB110-92756B from Novus Biologicals
|
||||||||
APCDD1 Antibody [DyLight 650] - NB110-92756C from Novus Biologicals
|
||||||||
APCDD1 Antibody [DyLight 550] - NB110-92756R from Novus Biologicals
|
||||||||
APCDD1 Antibody [HRP] - NB110-92756H from Novus Biologicals
|
||||||||
APCDD1 Antibody [DyLight 488] - NB110-92756G from Novus Biologicals
|
||||||||
APCDD1 Antibody [FITC] - NB110-92756F from Novus Biologicals
|
||||||||
APCDD1 Antibody [DyLight 405] - NB110-92756V from Novus Biologicals
|
||||||||
APCDD1 Antibody [Alexa Fluor (R) 700] - NB110-92756AF700 from Novus Biologicals
|
||||||||
APCDD1 Antibody [Alexa Fluor (R) 647] - NB110-92756AF647 from Novus Biologicals
|
||||||||
APCDD1 Antibody [Alexa Fluor (R) 488] - NB110-92756AF488 from Novus Biologicals
|
||||||||
APCDD1 Antibody [Alexa Fluor (R) 405] - NB110-92756AF405 from Novus Biologicals
|
||||||||
Rabbit Anti-APCDD1 Polyclonal Antibody - bs-1565R from Bioss
|
||||||||
Anti-APCDD1 antibody produced in mouse - SAB1408369 from Sigma-Aldrich
|
||||||||
APCDD1-Antibody-N-term - AP13356a from Abgent, a WuXi AppTec company
|
||||||||
APCDD1 Antibody - N-terminal region (OAAB09671) - OAAB09671 from Aviva Systems Biology
|
||||||||
Anti -APCDD1 (DRAPC1, Protein APCDD1, Adenomatosis Polyposis Coli Down-regulated 1Protein, FP7019) - 123392 from USBiological Life Science
|
||||||||
Anti -APCDD1, NT (APCDD1, DRAPC1, Protein APCDD1, Adenomatosis polyposis colidown-regulated 1 protein) - 031956 from USBiological Life Science
|