Gene Symbol |
MAN1A1
|
Entrez Gene |
4121
|
Alt Symbol |
HUMM3, HUMM9, MAN9
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
mannosidase, alpha, class 1A, member 1
|
Other Description |
Man9-mannosidase|alpha-1,2-mannosidase IA|man(9)-alpha-mannosidase|mannosyl-oligosaccharide 1,2-alpha-mannosidase IA|processing alpha-1,2-mannosidase IA
|
Swissprots |
Q9NU44 P33908 Q9UJI3 Q6P052 E7EU32
|
Accessions |
EAW48185 EAW48186 EAW48187 P33908 AK024588 AK025599 AK307383 BC065827 AAH65827 BQ008013 DA981556 XM_005266986 XP_005267043 XM_011535833 XP_011534135 XM_011535834 XP_011534136 XM_011535835 XP_011534137 NM_005907 NP_005898
|
Function |
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
|
Subcellular Location |
Golgi apparatus membrane; Single-pass type II membrane protein.
|
Top Pathways |
N-Glycan biosynthesis, Protein processing in endoplasmic reticulum
|