Gene Symbol | MAN1A1 |
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Entrez Gene | 4121 |
Alt Symbol | HUMM3, HUMM9, MAN9 |
Species | Human |
Gene Type | protein-coding |
Description | mannosidase, alpha, class 1A, member 1 |
Other Description | Man9-mannosidase|alpha-1,2-mannosidase IA|man(9)-alpha-mannosidase|mannosyl-oligosaccharide 1,2-alpha-mannosidase IA|processing alpha-1,2-mannosidase IA |
Swissprots | Q9NU44 P33908 Q9UJI3 Q6P052 E7EU32 |
Accessions | EAW48185 EAW48186 EAW48187 P33908 AK024588 AK025599 AK307383 BC065827 AAH65827 BQ008013 DA981556 XM_005266986 XP_005267043 XM_011535833 XP_011534135 XM_011535834 XP_011534136 XM_011535835 XP_011534137 NM_005907 NP_005898 |
Function | Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). |
Subcellular Location | Golgi apparatus membrane; Single-pass type II membrane protein. |
Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum |
MAN1A1 CRISPR/Cas9 KO Plasmid (h) - sc-410471 from Santa Cruz Biotechnology
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MAN1A1 HDR Plasmid (h) - sc-410471-HDR from Santa Cruz Biotechnology
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MAN1A1 Double Nickase Plasmid (h) - sc-410471-NIC from Santa Cruz Biotechnology
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MAN1A1 Double Nickase Plasmid (h2) - sc-410471-NIC-2 from Santa Cruz Biotechnology
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MAN1A1 CRISPR Activation Plasmid (h) - sc-410471-ACT from Santa Cruz Biotechnology
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MAN1A1 CRISPR Activation Plasmid (h2) - sc-410471-ACT-2 from Santa Cruz Biotechnology
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MAN1A1 Lentiviral Activation Particles (h) - sc-410471-LAC from Santa Cruz Biotechnology
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MAN1A1 Lentiviral Activation Particles (h2) - sc-410471-LAC-2 from Santa Cruz Biotechnology
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MAN1A1 siRNA (h) - sc-95638 from Santa Cruz Biotechnology
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MAN1A1 shRNA Plasmid (h) - sc-95638-SH from Santa Cruz Biotechnology
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MAN1A1 shRNA (h) Lentiviral Particles - sc-95638-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU142671 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12961 from Sigma-Aldrich
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MAN1A1 siRNA (Human) - CRH2798 from Cohesion Biosciences
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alpha 1 Mannosidase 1A RNAi - H00004121-R01 from Novus Biologicals
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shRNA set against Human MAN1A1 (NM_005907.3) - SHH337255 from Creative biogene
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Human MAN1A1 siRNA - orb263300 from Biorbyt
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MAN1A1 shRNA Plasmid (Human) - CHH2798 from Cohesion Biosciences
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MAN1A1 miRNA 3'UTR clone - MiUTR1H-06033 from Creative biogene
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