RAD51

Gene Symbol	RAD51
Entrez Gene	5888
Alt Symbol	BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA
Species	Human
Gene Type	protein-coding
Description	RAD51 recombinase
Other Description	BRCA1/BRCA2-containing complex, subunit 5|DNA repair protein RAD51 homolog 1|RAD51 homolog A|RecA, E. coli, homolog of|RecA-like protein|recombination protein A
Swissprots	Q9BV60 B0FXP0 B2R8T6 Q6FHX9 Q6ZNA8 Q06609
Accessions	AAD49705 AAF61901 AAF69145 AAN87149 EAW92431 EAW92432 EAW92433 EAW92434 EAW92435 Q06609 AK131299 BAD18467 AK291969 BAF84658 AK303089 BAG64200 AK313503 BAG36283 AU100170 AY425955 AAR07948 AY608888 AAT37157 BC001459 AAH01459 BT019705 AAV38511 CR536559 CAG38796 D13804 BAA02962 D14134 BAA03189 EU362635 ABY59731 XM_006720626 XP_006720689 XM_011521857 XP_011520159 XM_011521858 XP_011520160 XM_011521859 XP_011520161 XM_011521860 XP_011520162 XM_011521861 XP_011520163 XM_011521862 XP_011520164 NM_001164269 NP_001157741 NM_001164270 NP_001157742 NM_002875 NP_002866 NM_133487 NP_597994
Function	Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. {ECO:0000269|PubMed:12205100, ECO:0000269|PubMed:12442171, ECO:0000269|PubMed:18417535, ECO:0000269|PubMed:20231364, ECO:0000269|PubMed:20348101, ECO:0000269|PubMed:20413593, ECO:0000269|PubMed:23509288, ECO:0000269|PubMed:23754376}.
Subcellular Location	Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with RAD51AP1 and RPA2 to multiple nuclear foci upon induction of DNA damage. DNA damage induces an increase in nuclear levels. Together with FIGNL1, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) or camptothecin (CPT) treatment. Accumulated at sites of DNA damage in a SPIDR-dependent manner.
Tissue Specificity	Highly expressed in testis and thymus, followed by small intestine, placenta, colon, pancreas and ovary. Weakly expressed in breast.
Top Pathways	Homologous recombination, Pancreatic cancer, Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RAD51 / RECA ELISA Kit (Sandwich ELISA) - LS-F6761 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 0.312 ng/ml Range 0.312-20 ng/ml

Mouse/Human Phospho-RAD51 / RECA (Tyr315) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1408 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.312-20 ng/ml

Mouse/Human RAD51 / RECA ELISA Kit (Cell-Based ELISA) - LS-F2279 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.312-20 ng/ml

RAD51 Homolog (RAD51), Human, ELISA Kit - SEP750Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 0.081ng/mL Range 0.312-20ng/mL

RAD51 (Human) IP-WB Antibody Pair - H00005888-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

RAD51 (Human) Matched Antibody Pair - H00005888-AP11 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

RAD51 (Human) Matched Antibody Pair - H00005888-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

RAD51 Colorimetric Cell-Based ELISA Kit - CB5598 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

RAD51 (Phospho-Tyr315) Colorimetric Cell-Based ELISA Kit - CBP1437 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

DNA repair protein RAD51 homolog 1, ELISA Kit - MBS283498 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAD51 Homolog (RAD51), ELISA Kit - MBS9307320 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml Range 0.625 ng/ml - 20 ng/ml

RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) , ELISA Kit - MBS9321586 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.625ng/ml-20ng/ml.

ELISA Kit for RAD51 Homolog (RAD51) - SEP750Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.118ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for RAD51 Homolog (RAD51) - SEP750Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.118ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

RAD51 Homolog (RAD51), Human, ELISA Kit - DL-RAD51-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

RAD51 (Phospho-Tyr315) ELISA Kit - DEIA-XYA1967 from Creative Diagnostics Category ELISA Kit

Human RAD51 ELISA Kit - abx572422 from Abbexa Category ELISA Kit Sensitivity 0.081 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human RAD51 ELISA Kit - E032745 from Biobool Category ELISA Kit Sensitivity Typically less than 0.118ng/mL.

RAD51 ELISA Kit (Human) (OKCD01086) - OKCD01086 from Aviva Systems Biology Category ELISA Kit Prices $585.00 Sizes 96 wells Sensitivity < 0.118 ng/mL Range 0.312-20 ng/mL

anti-RAD51 antibody - ARG56558 from Arigo Biolaboratories Category ELISA Kit

anti-Rad51 antibody [51RAD01] - ARG62616 from Arigo Biolaboratories Category ELISA Kit

anti-RAD51 antibody - ARG55751 from Arigo Biolaboratories Category ELISA Kit

anti-RAD51 antibody - ARG53517 from Arigo Biolaboratories Category ELISA Kit

anti-RAD51 antibody (Ready-to-Use) - ARG53518 from Arigo Biolaboratories Category ELISA Kit

Human DNA repair protein RAD51 homolog 1 (RAD51) ELISA Kit - AE24529HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.118 ng/mL Range 0.312-20 ng/mL

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