Gene Symbol | HMGA2 |
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Entrez Gene | 8091 |
Alt Symbol | BABL, HMGI-C, HMGIC, LIPO, STQTL9 |
Species | Human |
Gene Type | protein-coding |
Description | high mobility group AT-hook 2 |
Other Description | High-mobility group protein HMGI-C|high mobility group protein HMGI-C|high-mobility group (nonhistone chromosomal) protein isoform I-C |
Swissprots | Q1M186 P52926 Q1M188 Q1M187 Q1M182 E7EP85 E7EWA2 Q1M185 |
Accessions | AAA68614 AAA96484 AAN64002 CAA03408 CAB59170 EAW97152 P52926 AB209853 BAD93090 AF533651 AF533652 AF533653 AAO48741 AF533654 AAO48742 AI290477 AK311399 AK311443 AK311447 AY601861 AAU43851 AY601862 AAU43852 AY601863 AAU43853 AY601864 AAU43854 AY601865 AAU43855 AY601866 AAU43856 AY601867 AAU43857 BC160115 AAI60115 BM782659 CA422738 CN334368 U28749 AAA68613 U29112 U29113 U29115 U29119 X92518 CAA63295 Z31595 CAA83472 NM_001300918 NP_001287847 NM_001300919 NP_001287848 NM_003483 NP_003474 NM_003484 NP_003475 NM_001015886 |
Function | Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. {ECO:0000269|PubMed:14645522}. |
Subcellular Location | Nucleus. |
Top Pathways | MicroRNAs in cancer, Transcriptional misregulation in cancer |
HMGI-C CRISPR/Cas9 KO Plasmid (h) - sc-401573 from Santa Cruz Biotechnology
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HMGI-C HDR Plasmid (h) - sc-401573-HDR from Santa Cruz Biotechnology
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HMGI-C Double Nickase Plasmid (h) - sc-401573-NIC from Santa Cruz Biotechnology
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HMGI-C Double Nickase Plasmid (h2) - sc-401573-NIC-2 from Santa Cruz Biotechnology
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HMGI-C CRISPR Activation Plasmid (h) - sc-401573-ACT from Santa Cruz Biotechnology
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HMGI-C CRISPR Activation Plasmid (h2) - sc-401573-ACT-2 from Santa Cruz Biotechnology
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HMGI-C Lentiviral Activation Particles (h) - sc-401573-LAC from Santa Cruz Biotechnology
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HMGI-C Lentiviral Activation Particles (h2) - sc-401573-LAC-2 from Santa Cruz Biotechnology
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HMGI-C siRNA (h) - sc-37994 from Santa Cruz Biotechnology
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HMGI-C shRNA Plasmid (h) - sc-37994-SH from Santa Cruz Biotechnology
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HMGI-C shRNA (h) Lentiviral Particles - sc-37994-V from Santa Cruz Biotechnology
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HMGA2 RNAi - H00008091-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN10159 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1265 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10159 from Sigma-Aldrich
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HMGA2 siRNA (Human) - CRH5366 from Cohesion Biosciences
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HMGA2 RNAi - H00008091-R01 from Novus Biologicals
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HMGA2 RNAi - H00008091-R03 from Novus Biologicals
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HMGA2 - MBS8238557 from MyBioSource
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Human HMGA2 siRNA - orb265868 from Biorbyt
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HMGA2 shRNA Plasmid (Human) - CHH5366 from Cohesion Biosciences
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