Gene Symbol | SLC2A1 |
---|---|
Entrez Gene | 6513 |
Alt Symbol | DYT17, DYT18, DYT9, EIG12, GLUT, GLUT-1, GLUT1, GLUT1DS, HTLVR, PED |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 2 (facilitated glucose transporter), member 1 |
Other Description | glucose transporter type 1, erythrocyte/brain|hepG2 glucose transporter|human T-cell leukemia virus (I and II) receptor|receptor for HTLV-1 and HTLV-2|solute carrier family 2, facilitated glucose transporter member 1 |
Swissprots | B2R620 O75535 Q147X2 P11166 A8K9S6 D3DPX0 |
Accessions | AAB61084 CAI23886 EAX07123 EAX07124 P11166 AB208987 BAD92224 AF070544 AAC28635 AK122999 BAG53842 AK292791 BAF85480 AK293306 BAG56827 AK296736 BAG59323 AK312403 BAG35317 AW137914 AY034633 AAK56795 BC118590 AAI18591 BC121804 AAI21805 BG682043 BI490999 BP314853 BQ948542 DA753077 K03195 AAA52571 NM_006516 NP_006507 |
Function | Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. {ECO:0000269|PubMed:18245775, ECO:0000269|PubMed:19449892}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Melanosome. Note=Localizes primarily at the cell surface. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues. {ECO:0000269|PubMed:23219802}. |
Top Pathways | Adipocytokine signaling pathway, Renal cell carcinoma, Bile secretion, HTLV-I infection, Central carbon metabolism in cancer |
SignalSilence ® Glut1 siRNA I - 14184 from Cell Signaling Technology
|
||||||||
Glut1 CRISPR/Cas9 KO Plasmid (h) - sc-400174 from Santa Cruz Biotechnology
|
||||||||
Glut1 HDR Plasmid (h) - sc-400174-HDR from Santa Cruz Biotechnology
|
||||||||
Glut1 Double Nickase Plasmid (h) - sc-400174-NIC from Santa Cruz Biotechnology
|
||||||||
Glut1 Double Nickase Plasmid (h2) - sc-400174-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Glut1 CRISPR Activation Plasmid (h) - sc-400174-ACT from Santa Cruz Biotechnology
|
||||||||
Glut1 CRISPR Activation Plasmid (h2) - sc-400174-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Glut1 Lentiviral Activation Particles (h) - sc-400174-LAC from Santa Cruz Biotechnology
|
||||||||
Glut1 Lentiviral Activation Particles (h2) - sc-400174-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Glut1 siRNA (h) - sc-35493 from Santa Cruz Biotechnology
|
||||||||
Glut1 shRNA Plasmid (h) - sc-35493-SH from Santa Cruz Biotechnology
|
||||||||
Glut1 shRNA (h) Lentiviral Particles - sc-35493-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU028011 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN1410 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN2346 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN1411 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN1409 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1411 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1410 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2346 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1409 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR08966 from Sigma-Aldrich
|
||||||||
SLC2A1 siRNA (Human) - CRH4408 from Cohesion Biosciences
|
||||||||
Glut1 RNAi - H00006513-R01 from Novus Biologicals
|
||||||||
SLC2A1 - MBS8222033 from MyBioSource
|