TFB2M

Gene Symbol TFB2M
Entrez Gene 64216
Alt Symbol Hkp1, mtTFB2
Species Human
Gene Type protein-coding
Description transcription factor B2, mitochondrial
Other Description HCV NS5A-transactivated protein 5|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2|dimethyladenosine transferase 2, mitochondrial|h-mtTFB|h-mtTFB2|hTFB2M|hepatitis C virus NS5A-transactivated protein 5|mitochondrial 12S rRNA dimethylase 2|mitochondrial transcription factor B2
Swissprots Q9H626 Q9H5Q4
Accessions EAW77149 EAW77150 EAW77151 EAW77152 EAW77153 Q9H5Q4 AF529366 AAQ09600 AK026314 BAB15441 AK026835 BAB15566 AK300238 BAG62006 BC003383 AAH03383 CK725134 DA038232 EU446518 ABZ92047 XM_011544248 XP_011542550 NM_022366 NP_071761
Function S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity. {ECO:0000269|PubMed:12068295, ECO:0000269|PubMed:12897151, ECO:0000269|PubMed:15526033, ECO:0000269|PubMed:20410300}.
Subcellular Location Mitochondrion.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:12068295}.

TFB2M CRISPR/Cas9 KO Plasmid (h) - sc-407156 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFB2M HDR Plasmid (h) - sc-407156-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFB2M Double Nickase Plasmid (h) - sc-407156-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFB2M Double Nickase Plasmid (h2) - sc-407156-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFB2M CRISPR Activation Plasmid (h) - sc-407156-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFB2M CRISPR Activation Plasmid (h2) - sc-407156-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFB2M Lentiviral Activation Particles (h) - sc-407156-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFB2M Lentiviral Activation Particles (h2) - sc-407156-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TFB2M siRNA (h) - sc-78569 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TFB2M shRNA Plasmid (h) - sc-78569-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TFB2M shRNA (h) Lentiviral Particles - sc-78569-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TFB2M RNAi - H00064216-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU005891 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21251 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21251 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TFB2M siRNA (Human) - CRJ1961 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TFB2M - MBS8219389 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TFB2M (NM_022366.2) - SHH426140 from Creative biogene

Category siRNA
Species Reactivities Human

TFB2M shRNA Plasmid (Human) - CHJ1961 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TFB2M miRNA 3'UTR clone - MiUTR3H-08931 from Creative biogene

Species Reactivities Human
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