KIF11

Gene Symbol KIF11
Entrez Gene 3832
Alt Symbol EG5, HKSP, KNSL1, MCLMR, TRIP5
Species Human
Gene Type protein-coding
Description kinesin family member 11
Other Description TR-interacting protein 5|TRIP-5|kinesin-like protein 1|kinesin-like protein KIF11|kinesin-like spindle protein HKSP|kinesin-related motor protein Eg5|thyroid receptor-interacting protein 5
Swissprots B2RMV3 Q15716 Q5VWX0 P52732 A0AV49
Accessions CAJ34547 CCD32721 EAW50089 P52732 AA504625 AA857025 AB208964 BAD92201 AK314258 BAG36923 BC050421 BC050667 BC126211 AAI26212 BC136474 AAI36475 BM742618 CU446438 DB078134 L40372 AAC41739 U37426 AAA86132 X85137 CAA59449 NM_004523 NP_004514
Function Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays. {ECO:0000269|PubMed:19001501}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19001501}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:19001501}.

Eg5 (E1L3W) Rabbit mAb - 14404 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E1L3W
Western blot analysis of extracts from A-431, MCF7, and COLO 205 cells using Eg5 (E1L3W) Rabbit mAb.

Eg5 Antibody - 7625 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Eg5 Antibody.

Eg5 (4H3-1F12) Mouse mAb - 4203 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 4H3-1F12
Western blot analysis of extracts form HeLa and 293 cells using Eg5 (4H3-1F12) Mouse mAb.

Eg5 (A-1) - sc-365681 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Eg5 (A-1): sc-365681. Western blot analysis of Eg5 expression in K-562 whole cell lysate.

Eg5 (D-7) - sc-393311 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Eg5 (D-7): sc-393311. Western blot analysis of Eg5 expression in M1 (A), MCF7 (B), A-431 (C), Jurkat (D), Raji (E) and K-562 (F) whole cell lysates. Note lack of reactivity in lanes B, C, D, E, and F.

Eg5 (F-1) - sc-374212 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Eg5 (F-1): sc-374212. Western blot analysis of Eg5 expression in HeLa (A) and K-562 (B) whole cell lysates.

Eg5 (C-20) - sc-31644 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Eg5 (C-20): sc-31644. Western blot analysis of Eg5 expression in HeLa whole cell lysate.

Eg5 (H-300) - sc-66872 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Eg5 (H-300): sc-66872. Western blot analysis of Eg5 expression in HeLa (A), MCF7 (B) and K-562 (C) whole cell lysates.

Eg5 (K-20) - sc-31643 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Eg5 (M-20) - sc-31646 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Eg5 (M-20): sc-31646. Western blot analysis of Eg5 expression in M1 whole cell lysate.

Eg5 (10C7/Eg5) - sc-53691 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Eg5 (10C7/Eg5): sc-53691. Western blot analysis of Eg5 expression in HeLa (A) and MCF7 (B) whole cell lysates.

Eg5 (20) - sc-136223 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal

Anti-Eg5 (phospho T927) antibody - ab61104 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Eg5 (phospho T927) antibody (ab61104) at 1/500 dilutionLane 1 : Extracts from COLO205 cells.Lane 2 : Extracts from COLO205 cells with the immunising peptide

Anti-Eg5 antibody - ab61199 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab61199 at 1/50 dilution staining Eg5 in human lung carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence (left) or presence (right) of the immunising peptide.

Anti-Eg5 antibody - ab37814 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Eg5 antibody (ab37814) at 1/250 dilutionLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate (ab7899)Lane 3 : A431 (Human epithelial carcinoma cell line) Whole Cell Lysate (ab7909)Lane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate (ab7902)Lysates/proteins at 10 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-Eg5 antibody - ab72413 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Eg5 antibody (ab72413) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µg

Anti-Eg5 antibody [4H3-1F12] - ab151186 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4H3-1F12
Immunofluorescence staining of HeLa cells using anti-Eg5 antibody (ab151186)  at a dilution of 1:200.

Anti-Eg5 antibody [EPR12280] - ab171963 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12280
Immunofluorescence analysis of HeLa cells, labeling Eg5 using ab171963 at a 1/100 dilution (red), and DAPI nuclear staining (blue).

Anti-Eg5 antibody [EPR12280-76] - ab181981 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12280-76
Immunofluorescence analysis of -20℃ acetone fixed HeLa cells labeling Eg5 with ab181981 at 1/100 dilution, followed by goat anti rabbit IgG (Dylight 555) at a 1/1000 dilution. Counter stained with Dapi.

Anti-Eg5 antibody [mAbcam 51976] - ab51976 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone mAbcam 51976
All lanes : Anti-Eg5 antibody [mAbcam 51976] (ab51976) at 5 µg/mlLane 1 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lane 2 : A431 (Human epithelial carcinoma cell line) Whole Cell LysateLane 3 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryRabbit polyclonal to Mouse IgG - H&L (HRP) at 1/2000 dilutionPerformed under reducing conditions.

Anti-Eg5 antibody - C-terminal - ab137535 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Eg5 antibody - C-terminal (ab137535) at 1/5000 dilutionLane 1 : H1299 cell lysateLane 2 : HeLaS3 cell lysateLysates/proteins at 30 µg per lane.

Anti-Eg5 antibody - N-terminal - ab95097 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Eg5 antibody - N-terminal (ab95097) at 1/100 dilution + CHO cell line lysates at 35 µg

Anti-KIF11 / EG5 Antibody (clone 2A5) - LS-C179844 from LifeSpan Bioscience

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A5

Anti-KIF11 / EG5 Antibody (aa200-500) - LS-C189711 from LifeSpan Bioscience

Prices $335.00
Sizes 25 µg
Host Mouse
Clonality Monoclonal

Anti-KIF11 / EG5 Antibody - LS-C209183 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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