| Gene Symbol |
KIF11
|
| Entrez Gene |
3832
|
| Alt Symbol |
EG5, HKSP, KNSL1, MCLMR, TRIP5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kinesin family member 11
|
| Other Description |
TR-interacting protein 5|TRIP-5|kinesin-like protein 1|kinesin-like protein KIF11|kinesin-like spindle protein HKSP|kinesin-related motor protein Eg5|thyroid receptor-interacting protein 5
|
| Swissprots |
B2RMV3 Q15716 Q5VWX0 P52732 A0AV49
|
| Accessions |
CAJ34547 CCD32721 EAW50089 P52732 AA504625 AA857025 AB208964 BAD92201 AK314258 BAG36923 BC050421 BC050667 BC126211 AAI26212 BC136474 AAI36475 BM742618 CU446438 DB078134 L40372 AAC41739 U37426 AAA86132 X85137 CAA59449 NM_004523 NP_004514
|
| Function |
Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays. {ECO:0000269|PubMed:19001501}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19001501}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:19001501}.
|
![Western Blot: Eg5 Overexpression Lysate (Adult Normal) [NBL1-12284] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Eg5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1256_Eg5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12284-img0002.jpg)