| Gene Symbol |
BLOC1S5
|
| Entrez Gene |
63915
|
| Alt Symbol |
BLOS5, MU, MUTED
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
biogenesis of lysosomal organelles complex-1, subunit 5, muted
|
| Other Description |
BLOC-1 subunit 5|biogenesis of lysosome-related organelles complex 1 subunit 5|muted homolog|protein Muted homolog
|
| Swissprots |
Q9NU16 Q8TDH9 Q0VDJ7 Q5THS1 Q68D56 B4DVM2 Q0VDJ6 Q8N5F9
|
| Accessions |
EAW55225 Q8TDH9 AA653396 AF426434 AAL99385 AK025442 AK301142 BAG62734 AK311385 BC032438 AAH32438 BC119644 AAI19645 BC119645 AAI19646 BM829259 BX647336 CR749569 CAH18364 DA635930 NM_001199322 NP_001186251 NM_001199323 NP_001186252 NM_201280 NP_958437
|
| Function |
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. {ECO:0000269|PubMed:17182842}.
|