Gene Symbol | BLOC1S5 |
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Entrez Gene | 63915 |
Alt Symbol | BLOS5, MU, MUTED |
Species | Human |
Gene Type | protein-coding |
Description | biogenesis of lysosomal organelles complex-1, subunit 5, muted |
Other Description | BLOC-1 subunit 5|biogenesis of lysosome-related organelles complex 1 subunit 5|muted homolog|protein Muted homolog |
Swissprots | Q9NU16 Q8TDH9 Q0VDJ7 Q5THS1 Q68D56 B4DVM2 Q0VDJ6 Q8N5F9 |
Accessions | EAW55225 Q8TDH9 AA653396 AF426434 AAL99385 AK025442 AK301142 BAG62734 AK311385 BC032438 AAH32438 BC119644 AAI19645 BC119645 AAI19646 BM829259 BX647336 CR749569 CAH18364 DA635930 NM_001199322 NP_001186251 NM_001199323 NP_001186252 NM_201280 NP_958437 |
Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. {ECO:0000269|PubMed:17182842}. |
MISSION® esiRNA - EHU098691 from Sigma-Aldrich
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MISSION® esiRNA - EHU093681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14773 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14773 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10244 from Sigma-Aldrich
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BLOC1S5 siRNA (Human) - CRJ1858 from Cohesion Biosciences
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Muted CRISPR/Cas9 KO Plasmid (h) - sc-416251 from Santa Cruz Biotechnology
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Muted HDR Plasmid (h) - sc-416251-HDR from Santa Cruz Biotechnology
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Muted Double Nickase Plasmid (h) - sc-416251-NIC from Santa Cruz Biotechnology
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Muted Double Nickase Plasmid (h2) - sc-416251-NIC-2 from Santa Cruz Biotechnology
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Muted CRISPR Activation Plasmid (h) - sc-416251-ACT from Santa Cruz Biotechnology
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Muted CRISPR Activation Plasmid (h2) - sc-416251-ACT-2 from Santa Cruz Biotechnology
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Muted Lentiviral Activation Particles (h) - sc-416251-LAC from Santa Cruz Biotechnology
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Muted Lentiviral Activation Particles (h2) - sc-416251-LAC-2 from Santa Cruz Biotechnology
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Muted siRNA (h) - sc-61108 from Santa Cruz Biotechnology
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Muted shRNA Plasmid (h) - sc-61108-SH from Santa Cruz Biotechnology
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Muted shRNA (h) Lentiviral Particles - sc-61108-V from Santa Cruz Biotechnology
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BLOC1S5 - MBS8214412 from MyBioSource
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shRNA set against Human MUTED (NM_001199322.1) - SHH347220 from Creative biogene
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Human BLOC1S5 siRNA - orb272359 from Biorbyt
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BLOC1S5 shRNA Plasmid (Human) - CHJ1858 from Cohesion Biosciences
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BLOC1S5 miRNA 3'UTR clone - MiUTR3H-09120 from Creative biogene
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