ELF5

Gene Symbol	ELF5
Entrez Gene	2001
Alt Symbol	ESE2
Species	Human
Gene Type	protein-coding
Description	E74-like factor 5 (ets domain transcription factor)
Other Description	ETS-related transcription factor Elf-5|epithelium-restricted ESE-1-related Ets factor|epithelium-specific Ets transcription factor 2
Swissprots	A8K452 Q9UKW5 Q8N2K9 O95175 Q96QY3 A6XAE6 Q9UKW6
Accessions	CAF86494 EAW68168 EAW68169 Q9UKW6 AF049703 AAC79755 AF115402 AAD22960 AF115403 AAD22961 AK074633 BAC11101 AK075197 BAG52081 AK290808 BAF83497 AK290817 BAF83506 AK312537 BAG35436 BC029743 AAH29743 BG260616 BP358543 DA630849 DQ123839 AAZ98848 DQ891137 ABM82063 DQ894316 ABM85242 NM_001243080 NP_001230009 NM_001243081 NP_001230010 NM_001422 NP_001413 NM_198381 NP_938195
Function	Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation. {ECO:0000269|PubMed:10506207}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00237}.
Tissue Specificity	Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tissues. In the kidney, only isoform 1 was expressed, while prostate expressed both isoforms, with levels of isoform 2 being higher. Expression is up-regulated during keratinocyte differentiation. Several epithelial carcinoma cell lines showed lack of expression. {ECO:0000269|PubMed:10506207, ECO:0000269|PubMed:9840936}.
Top Pathways	Prolactin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ELF5 full length protein - ab132116 from Abcam Category Protein Source Wheat germ Species Human

Human ELF5 peptide - ab23219 from Abcam Category Peptide Species Human

Human ELF5 protein fragment - ab116821 from Abcam Category Protein Source Wheat germ Species Human

ELF5 Antibody Blocking Peptide - LS-E25384 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ELF5 Antibody Blocking Peptide - LS-E8920 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ELF5 Antibody Blocking Peptide - LS-E13288 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ELF5 Partial Recombinant Protein - H00002001-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ELF5 Recombinant Protein - H00002001-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

ELF5-Antibody-Center-Blocking-Peptide - BP7394c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ELF5 blocking peptide - GTX13581-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

ELF5 peptide - orb217246 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

ELF5 Blocking Peptide - abx062577 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine

ELF5 Peptide - AC21-0212-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ELF5 / ESE2 - H00002001-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ELF5 / ESE2 - H00002001-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ELF5 / ESE2 - H00002001-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ELF5 / ESE2 - H00002001-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ELF5 Peptide - 45-528P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

ELF5 fusion protein - Ag14861 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

ELF5 fusion protein - Ag3762 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ELF5 - ELF5-28286TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human ELF5, GST-tagged - ELF5-904H from Creative Biomart Category Protein Source wheat germ

Recombinant Human ELF5, GST-tagged - ELF5-902H from Creative Biomart Category Protein Source wheat germ

Recombinant Human ELF5, His-tagged - ELF5-12402H from Creative Biomart Category Protein Source E.coli Species Human

ELF5 Blocking Peptide - CBP1383 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine

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