SLC38A1

Gene Symbol SLC38A1
Entrez Gene 81539
Alt Symbol ATA1, NAT2, SAT1, SNAT1
Species Human
Gene Type protein-coding
Description solute carrier family 38, member 1
Other Description N-system amino acid transporter 2|amino acid transporter A1|amino acid transporter system A1|sodium-coupled neutral amino acid transporter 1|system A amino acid transporter 1|system N amino acid transporter 1
Swissprots Q9H2Q2 Q9H2H9 Q8NC61 Q96JX2 Q8NCF8
Accessions EAW57895 EAW57896 EAW57897 EAW57898 EAW57899 Q9H2H9 AA740867 AA864710 AF247166 AAG44546 AF271070 AAG39354 AK024263 AK025900 AK027825 BAB55394 AK056670 AK074758 BAC11186 AK074797 BAC11215 AK074851 AK074949 BAC11310 AK130314 AK225639 AK225778 AK308129 AK309410 AK313731 BC010620 AAH10620 BQ019472 BX647547 BX648495 BX648676 DB229647 DQ891017 ABM81943 EU176550 ABW03351 S77359 XM_011538784 XP_011537086 XM_011538785 XP_011537087 XM_011538786 XP_011537088 XM_011538787 XP_011537089 NM_001077484 NP_001070952 NM_001278387 NP_001265316 NM_001278388 NP_001265317 NM_001278389 NP_001265318 NM_001278390 NP_001265319 NM_030674 NP_109599
Function Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA. {ECO:0000269|PubMed:10891391}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15054072}; Multi-pass membrane protein {ECO:0000269|PubMed:15054072}. Note=Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis. {ECO:0000269|PubMed:10891391, ECO:0000269|PubMed:12388062, ECO:0000269|PubMed:15054072, ECO:0000269|PubMed:16148032}.
Top Pathways GABAergic synapse, Glutamatergic synapse

SNAT1 (C-12) - sc-33441 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SNAT1 (C-12): sc-33441. Western blot analysis of SNAT1 expression in Ramos whole cell lysate.

SNAT1 (H-9) - sc-137032 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SNAT1 (H-9): sc-137032. Western blot analysis of SNAT1 expression in non-transfected: sc-117752 (A) and human SNAT1 transfected: sc-111142 (B) 293T whole cell lysates.

SNAT1 (T-20) - sc-33439 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SNAT1 (H-60) - sc-67080 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SNAT1 (H-60): sc-67080. Western blot analysis of SNAT1 expression in NAMALWA (A) and Ramos (B) whole cell lysates and human recombinant SNAT1 fusion protein (C).

Anti-SLC38A1 antibody - ab104684 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-SLC38A1 antibody [S104-32] - ab134268 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32
Anti-SLC38A1 antibody [S104-32] (ab134268) at 1/1000 dilution + Rat brain membrane tissue lysateSecondaryGoat anti-mouse IgG HRP

Anti-SLC38A1 / NaT2 Antibody (aa211-260) - LS-C40425 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SLC38A1 antibody LS-C40425 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, Atto 488) - LS-C231672 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, Atto 390) - LS-C231673 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, Atto 565) - LS-C231674 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, Atto 594) - LS-C231675 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, Atto 633) - LS-C231676 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, Atto 655) - LS-C231678 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa301-350) - LS-C40426 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SLC38A1 antibody LS-C40426 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, Atto 700) - LS-C231681 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, APC) - LS-C231683 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, Atto 680) - LS-C231680 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, AP) - LS-C231682 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, Biotin) - LS-C231684 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, FITC) - LS-C231685 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, PerCP) - LS-C231688 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, PE, Atto 594) - LS-C231687 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, RPE) - LS-C231689 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32) - LS-C309132 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32

Anti-SLC38A1 / NaT2 Antibody (aa1-63, clone S104-32, SA) - LS-C231692 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S104-32
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