SLC38A1

Gene Symbol SLC38A1
Entrez Gene 81539
Alt Symbol ATA1, NAT2, SAT1, SNAT1
Species Human
Gene Type protein-coding
Description solute carrier family 38, member 1
Other Description N-system amino acid transporter 2|amino acid transporter A1|amino acid transporter system A1|sodium-coupled neutral amino acid transporter 1|system A amino acid transporter 1|system N amino acid transporter 1
Swissprots Q9H2Q2 Q9H2H9 Q8NC61 Q96JX2 Q8NCF8
Accessions EAW57895 EAW57896 EAW57897 EAW57898 EAW57899 Q9H2H9 AA740867 AA864710 AF247166 AAG44546 AF271070 AAG39354 AK024263 AK025900 AK027825 BAB55394 AK056670 AK074758 BAC11186 AK074797 BAC11215 AK074851 AK074949 BAC11310 AK130314 AK225639 AK225778 AK308129 AK309410 AK313731 BC010620 AAH10620 BQ019472 BX647547 BX648495 BX648676 DB229647 DQ891017 ABM81943 EU176550 ABW03351 S77359 XM_011538784 XP_011537086 XM_011538785 XP_011537087 XM_011538786 XP_011537088 XM_011538787 XP_011537089 NM_001077484 NP_001070952 NM_001278387 NP_001265316 NM_001278388 NP_001265317 NM_001278389 NP_001265318 NM_001278390 NP_001265319 NM_030674 NP_109599
Function Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA. {ECO:0000269|PubMed:10891391}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15054072}; Multi-pass membrane protein {ECO:0000269|PubMed:15054072}. Note=Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis. {ECO:0000269|PubMed:10891391, ECO:0000269|PubMed:12388062, ECO:0000269|PubMed:15054072, ECO:0000269|PubMed:16148032}.
Top Pathways GABAergic synapse, Glutamatergic synapse

SNAT1 CRISPR/Cas9 KO Plasmid (h) - sc-404674 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNAT1 HDR Plasmid (h) - sc-404674-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNAT1 Double Nickase Plasmid (h) - sc-404674-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNAT1 Double Nickase Plasmid (h2) - sc-404674-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNAT1 CRISPR Activation Plasmid (h) - sc-404674-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNAT1 CRISPR Activation Plasmid (h2) - sc-404674-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNAT1 Lentiviral Activation Particles (h) - sc-404674-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNAT1 Lentiviral Activation Particles (h2) - sc-404674-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNAT1 siRNA (h) - sc-44972 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SNAT1 shRNA Plasmid (h) - sc-44972-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SNAT1 shRNA (h) Lentiviral Particles - sc-44972-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU068671 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19603 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19603 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SLC38A1 siRNA (Human) - CRJ2984 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC38A1 RNAi - H00081539-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SLC38A1 - MBS8221800 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC38A1 (NM_030674.3) - SHH410920 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SLC38A1(NM_001077484.1) - SHH221712 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC38A1 siRNA - orb273485 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC38A1 shRNA Plasmid (Human) - CHJ2984 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC38A1 miRNA 3'UTR clone - MiUTR1H-09553 from Creative biogene

Species Reactivities Human
Search more