| Gene Symbol |
ZP1
|
| Entrez Gene |
22917
|
| Alt Symbol |
HEL163, OOMD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zona pellucida glycoprotein 1 (sperm receptor)
|
| Other Description |
epididymis luminal protein 163|zona pellucida sperm-binding protein 1
|
| Swissprots |
P60852
|
| Accessions |
AHY84697 EAW73903 P60852 AI208352 AI766401 BC067899 AAH67899 CR741030 EU794684 ACJ13738 XM_011544852 XP_011543154 XM_011544853 XP_011543155 NM_207341 NP_997224
|
| Function |
The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.
|
| Subcellular Location |
Processed zona pellucida sperm-binding protein 1: Secreted, extracellular space, extracellular matrix. Note=The glycoproteinaceous translucent extracellular matrix that surrounds the mammalian oocyte is called zona pellucida.
|
| Tissue Specificity |
Oocytes.
|