Gene Symbol | ZP1 |
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Entrez Gene | 22917 |
Alt Symbol | HEL163, OOMD |
Species | Human |
Gene Type | protein-coding |
Description | zona pellucida glycoprotein 1 (sperm receptor) |
Other Description | epididymis luminal protein 163|zona pellucida sperm-binding protein 1 |
Swissprots | P60852 |
Accessions | AHY84697 EAW73903 P60852 AI208352 AI766401 BC067899 AAH67899 CR741030 EU794684 ACJ13738 XM_011544852 XP_011543154 XM_011544853 XP_011543155 NM_207341 NP_997224 |
Function | The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida. |
Subcellular Location | Processed zona pellucida sperm-binding protein 1: Secreted, extracellular space, extracellular matrix. Note=The glycoproteinaceous translucent extracellular matrix that surrounds the mammalian oocyte is called zona pellucida. |
Tissue Specificity | Oocytes. |
ZP1 CRISPR/Cas9 KO Plasmid (h) - sc-403636 from Santa Cruz Biotechnology
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ZP1 HDR Plasmid (h) - sc-403636-HDR from Santa Cruz Biotechnology
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ZP1 Double Nickase Plasmid (h) - sc-403636-NIC from Santa Cruz Biotechnology
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ZP1 Double Nickase Plasmid (h2) - sc-403636-NIC-2 from Santa Cruz Biotechnology
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ZP1 CRISPR Activation Plasmid (h) - sc-403636-ACT from Santa Cruz Biotechnology
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ZP1 CRISPR Activation Plasmid (h2) - sc-403636-ACT-2 from Santa Cruz Biotechnology
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ZP1 Lentiviral Activation Particles (h) - sc-403636-LAC from Santa Cruz Biotechnology
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ZP1 Lentiviral Activation Particles (h2) - sc-403636-LAC-2 from Santa Cruz Biotechnology
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ZP1 siRNA (h) - sc-61831 from Santa Cruz Biotechnology
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ZP1 shRNA Plasmid (h) - sc-61831-SH from Santa Cruz Biotechnology
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ZP1 shRNA (h) Lentiviral Particles - sc-61831-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU110311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23787 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23787 from Sigma-Aldrich
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ZP1 siRNA (Human) - CRH7870 from Cohesion Biosciences
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ZP1 - MBS827342 from MyBioSource
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shRNA set against Human ZP1 (NM_207341.2) - SHH455720 from Creative biogene
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shRNA set against Human ZP1(NM_207341.2) - SHL162480 from Creative biogene
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ZP1 shRNA Plasmid (Human) - CHH7870 from Cohesion Biosciences
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ZP1 miRNA 3'UTR clone - MiUTR1H-11750 from Creative biogene
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