Gene Symbol |
KERA
|
Entrez Gene |
11081
|
Alt Symbol |
CNA2, KTN, SLRR2B
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
keratocan
|
Other Description |
keratan sulfate proteoglycan keratocan
|
Swissprots |
O60938
|
Accessions |
AAC17741 EAW97448 O60938 AF063301 AAC16390 AF205403 AAF69126 AK314990 BAG37486 BC032667 AAH32667 BM722433 CV571245 DQ890891 ABM81817 DQ894046 ABM84972 XM_011537781 XP_011536083 NM_007035 NP_008966
|
Function |
May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}.
|
Tissue Specificity |
Cornea. Increased expression in the stroma of keratoconus corneas. Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen. {ECO:0000269|PubMed:11683372}.
|