Gene Symbol | KERA |
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Entrez Gene | 11081 |
Alt Symbol | CNA2, KTN, SLRR2B |
Species | Human |
Gene Type | protein-coding |
Description | keratocan |
Other Description | keratan sulfate proteoglycan keratocan |
Swissprots | O60938 |
Accessions | AAC17741 EAW97448 O60938 AF063301 AAC16390 AF205403 AAF69126 AK314990 BAG37486 BC032667 AAH32667 BM722433 CV571245 DQ890891 ABM81817 DQ894046 ABM84972 XM_011537781 XP_011536083 NM_007035 NP_008966 |
Function | May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Cornea. Increased expression in the stroma of keratoconus corneas. Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen. {ECO:0000269|PubMed:11683372}. |
Keratocan CRISPR/Cas9 KO Plasmid (h) - sc-416323 from Santa Cruz Biotechnology
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Keratocan HDR Plasmid (h) - sc-416323-HDR from Santa Cruz Biotechnology
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Keratocan Double Nickase Plasmid (h) - sc-416323-NIC from Santa Cruz Biotechnology
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Keratocan Double Nickase Plasmid (h2) - sc-416323-NIC-2 from Santa Cruz Biotechnology
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Keratocan CRISPR Activation Plasmid (h) - sc-416323-ACT from Santa Cruz Biotechnology
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Keratocan CRISPR Activation Plasmid (h2) - sc-416323-ACT-2 from Santa Cruz Biotechnology
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Keratocan Lentiviral Activation Particles (h) - sc-416323-LAC from Santa Cruz Biotechnology
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Keratocan Lentiviral Activation Particles (h2) - sc-416323-LAC-2 from Santa Cruz Biotechnology
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Keratocan siRNA (h) - sc-44701 from Santa Cruz Biotechnology
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Keratocan shRNA Plasmid (h) - sc-44701-SH from Santa Cruz Biotechnology
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Keratocan shRNA (h) Lentiviral Particles - sc-44701-V from Santa Cruz Biotechnology
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KERA RNAi - H00011081-R01 from Novus Biologicals
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MISSION® esiRNA - EHU016581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11042 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11042 from Sigma-Aldrich
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KERA siRNA (Human) - CRH7578 from Cohesion Biosciences
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shRNA set against Human KERA (NM_007035.3) - SHH324347 from Creative biogene
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shRNA set against Human KERA(NM_007035.3) - SHL194130 from Creative biogene
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KERA shRNA Plasmid (Human) - CHH7578 from Cohesion Biosciences
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KERA miRNA 3'UTR clone - MiUTR1H-05191 from Creative biogene
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