| Gene Symbol |
FAT1
|
| Entrez Gene |
2195
|
| Alt Symbol |
CDHF7, CDHR8, FAT, ME5, hFat1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
FAT atypical cadherin 1
|
| Other Description |
FAT tumor suppressor 1|FAT tumor suppressor homolog 1|cadherin ME5|cadherin family member 7|cadherin-related family member 8|cadherin-related tumor suppressor homolog|protein fat homolog|protocadherin Fat 1
|
| Swissprots |
Q14517
|
| Accessions |
CCQ43310 EAX04614 EAX04615 EAX04616 Q14517 AK307938 BC012432 BF327563 BP363658 BU729008 CD642620 CN289962 D88798 BAA21568 EF139845 X87241 CAA60685 XM_005262834 XP_005262891 XM_005262835 XP_005262892 XM_006714139 XP_006714202 NM_005245 NP_005236
|
| Function |
Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact. {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:15922730}; Single-pass type I membrane protein {ECO:0000269|PubMed:15922730}. Nucleus {ECO:0000269|PubMed:15922730}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:15922730}.
|
| Tissue Specificity |
Expressed in many epithelial and some endothelial and smooth muscle cells.
|