Gene Symbol | FAT1 |
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Entrez Gene | 2195 |
Alt Symbol | CDHF7, CDHR8, FAT, ME5, hFat1 |
Species | Human |
Gene Type | protein-coding |
Description | FAT atypical cadherin 1 |
Other Description | FAT tumor suppressor 1|FAT tumor suppressor homolog 1|cadherin ME5|cadherin family member 7|cadherin-related family member 8|cadherin-related tumor suppressor homolog|protein fat homolog|protocadherin Fat 1 |
Swissprots | Q14517 |
Accessions | CCQ43310 EAX04614 EAX04615 EAX04616 Q14517 AK307938 BC012432 BF327563 BP363658 BU729008 CD642620 CN289962 D88798 BAA21568 EF139845 X87241 CAA60685 XM_005262834 XP_005262891 XM_005262835 XP_005262892 XM_006714139 XP_006714202 NM_005245 NP_005236 |
Function | Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:15922730}; Single-pass type I membrane protein {ECO:0000269|PubMed:15922730}. Nucleus {ECO:0000269|PubMed:15922730}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:15922730}. |
Tissue Specificity | Expressed in many epithelial and some endothelial and smooth muscle cells. |
FAT1 CRISPR/Cas9 KO Plasmid (h) - sc-410778 from Santa Cruz Biotechnology
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FAT1 HDR Plasmid (h) - sc-410778-HDR from Santa Cruz Biotechnology
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FAT1 Double Nickase Plasmid (h) - sc-410778-NIC from Santa Cruz Biotechnology
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FAT1 Double Nickase Plasmid (h2) - sc-410778-NIC-2 from Santa Cruz Biotechnology
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FAT1 CRISPR Activation Plasmid (h) - sc-410778-ACT from Santa Cruz Biotechnology
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FAT1 CRISPR Activation Plasmid (h2) - sc-410778-ACT-2 from Santa Cruz Biotechnology
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FAT1 Lentiviral Activation Particles (h) - sc-410778-LAC from Santa Cruz Biotechnology
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FAT1 Lentiviral Activation Particles (h2) - sc-410778-LAC-2 from Santa Cruz Biotechnology
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FAT1 siRNA (h) - sc-88872 from Santa Cruz Biotechnology
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FAT1 shRNA Plasmid (h) - sc-88872-SH from Santa Cruz Biotechnology
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FAT1 shRNA (h) Lentiviral Particles - sc-88872-V from Santa Cruz Biotechnology
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FAT1 RNAi - H00002195-R01 from Novus Biologicals
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MISSION® esiRNA - EHU046081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8494 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8494 from Sigma-Aldrich
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FAT1 siRNA (Human) - CRH1531 from Cohesion Biosciences
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FAT1 - MBS8224469 from MyBioSource
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shRNA set against Human FAT1 (NM_005245.3) - SHH292573 from Creative biogene
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shRNA set against Human FAT(NM_005245.3) - SHH049799 from Creative biogene
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Human FAT1 siRNA - orb262033 from Biorbyt
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FAT1 shRNA Plasmid (Human) - CHH1531 from Cohesion Biosciences
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FAT1 miRNA 3'UTR clone - MiUTR1H-03521 from Creative biogene
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